SERPINA3: serpin family A member 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1as4 chain A
1as4 chain B
1qmn chain A
2ach chain A
2ach chain B
3caa chain A
3caa chain B
3dlw chain A
4caa chain A
4caa chain B
5om2 chain A
5om2 chain B
5om3 chain A
5om3 chain B
5om5 chain A
5om5 chain B
5om6 chain A
5om6 chain B
5om6 chain C
5om6 chain D
5om7 chain A
5om7 chain B
5om8 chain A
5om8 chain B
6ftp chain A
6ftp chain B
6hgd chain A
6hgd chain B
6hge chain A
6hge chain B
6hge chain C
6hge chain D
6hgf chain A
6hgf chain B
6hgg chain A
6hgg chain B
6hgh chain A
6hgh chain B
6hgi chain A
6hgi chain B
6hgj chain A
6hgj chain B
6hgk chain A
6hgk chain B
6hgl chain A
6hgl chain B
6hgm chain A
6hgm chain B
6hgn chain A
6hgn chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S129 LLRTLNQS SDELQLS 2 43 - - 21 4 - - - - 12 6 - - - - - - - - - - S130 LRTLNQSS DELQLSM 2 43 - - 21 4 - - - - 12 6 - - - - - - - - - - S136 SSDELQLS MGNAMFV 6 62 9 - 5 4 - - 9 - 11 7 5 4 4 4 - - - - - - S148 MFVKEQLS LLDRFTE 4 45 9 - - - - - 9 - 11 7 5 4 - - - - - - - - T154 LSLLDRFT EDAKRLY 4 45 9 - - - - - 9 - 11 7 5 4 - - - - - - - - S355 GARNLAVS QVVHKAV 1 8 - - - - - - - - - - - - 4 4 - - - - - - S384 AVKITLLS ALVETRT 5 105 - - 21 12 - - 37 - 5 4 10 8 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S129 LLRTLNQS SDELQLS - - - - - - - - - - - S130 LRTLNQSS DELQLSM - - - - - - - - - - - S136 SSDELQLS MGNAMFV - - - - - - - - - - - S148 MFVKEQLS LLDRFTE - - - - - - - - - - - T154 LSLLDRFT EDAKRLY - - - - - - - - - - - S355 GARNLAVS QVVHKAV - - - - - - - - - - - S384 AVKITLLS ALVETRT -0.75 - -0.75 - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S129
S130
S136
S148
T154
S355
S384
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation CCRCC S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation COAD S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation GBM S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation HNSCC S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation LSCC S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation LUAD S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation OV S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation PDAC S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation UCEC S129 S130 S136 S148 T154 S355 S384 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S129
S130
S136
S148
T154
S355
S384
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S129
S130
S136
S148
T154
S355
S384
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.