SERPINA1: serpin family A member 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1atu chain A
1d5s chain A
1d5s chain B
1ezx chain A
1ezx chain B
1hp7 chain A
1iz2 chain A
1kct chain A
1oo8 chain A
1oph chain A
1psi chain A
1qlp chain A
1qmb chain A
1qmb chain B
2d26 chain A
2d26 chain B
2qug chain A
3cwl chain A
3cwm chain A
3drm chain A
3dru chain A
3dru chain B
3dru chain C
3ndd chain A
3ndd chain B
3ndf chain A
3ndf chain B
3ne4 chain A
3t1p chain A
4pyw chain A
5io1 chain A
5io1 chain B
5nbu chain A
5nbv chain A
6hx4 chain A
6hx4 chain B
6i3z chain A
6i3z chain B
6i4v chain A
6i7u chain A
6iay chain A
6rod chain A
7ael chain AAA
7api chain A
7api chain B
7npk chain A
7npl chain A
8api chain A
8api chain B
9api chain A
9api chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T37 DAAQKTDT SHHDQDH 9 487 - - 5 4 51 57 81 - 31 15 29 27 14 11 14 3 77 31 23 14 S38 AAQKTDTS HHDQDHP 9 165 8 - 5 4 13 14 18 - 31 17 10 9 8 9 7 1 8 3 - - S60 NLAEFAFS LYRQLAH 2 35 - - 8 8 - - - - - - 10 9 - - - - - - - - T96 SLGTKADT HDEILEG 2 25 - - 8 8 - - - - - - - - - - - - - - - 9 T109 EGLNFNLT EIPEAQI 3 34 - - 4 4 - - - - - - - - 9 8 - - - - - 9 S132 RTLNQPDS QLQLTTG 1 8 - - - - - - - - - - - - 4 4 - - - - - - S145 TGNGLFLS EGLKLVD 1 10 - - - - - - - - 6 4 - - - - - - - - - - T238 DFHVDQVT TVKVPMM 1 8 - - 4 4 - - - - - - - - - - - - - - - - S260 IQHCKKLS SWVLLMK 1 8 - - - - - - - - 5 3 - - - - - - - - - - S261 QHCKKLSS WVLLMKY 1 8 - - - - - - - - 5 3 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T37 DAAQKTDT SHHDQDH -2.1e-10 - - -1.9e-8 - -1.3e-7 -7.3e-9 - - 7.5e-8 -3.6e-3 S38 AAQKTDTS HHDQDHP -2.2e-7 - - - - -2.2e-7 - - - - - S60 NLAEFAFS LYRQLAH - - - - - - - - - - - T96 SLGTKADT HDEILEG - - - - - - - - - - - T109 EGLNFNLT EIPEAQI - - - - - - - - - - - S132 RTLNQPDS QLQLTTG - - - - - - - - - - - S145 TGNGLFLS EGLKLVD - - - - - - - - - - - T238 DFHVDQVT TVKVPMM - - - - - - - - - - - S260 IQHCKKLS SWVLLMK - - - - - - - - - - - S261 QHCKKLSS WVLLMKY - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T37
S38
S60
T96
T109
S132
S145
T238
S260
S261
Y268
T273
S307
S309
S316
T318
S325
T333
S337
S343
T346
S354
S383
T416
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation CCRCC T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation COAD T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation GBM T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation HNSCC T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation LSCC T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation LUAD T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation OV T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation PDAC T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation UCEC T37 S38 S60 T96 T109 S132 S145 T238 S260 S261 Y268 T273 S307 S309 S316 T318 S325 T333 S337 S343 T346 S354 S383 T416 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T37
S38
S60
T96
T109
S132
S145
T238
S260
S261
Y268
T273
S307
S309
S316
T318
S325
T333
S337
S343
T346
S354
S383
T416
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T37
S38
S60
T96
T109
S132
S145
T238
S260
S261
Y268
T273
S307
S309
S316
T318
S325
T333
S337
S343
T346
S354
S383
T416
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.