NME1: NME/NM23 nucleoside diphosphate kinase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1jxv chain A
1jxv chain B
1jxv chain C
1jxv chain D
1jxv chain E
1jxv chain F
1ucn chain A
1ucn chain B
1ucn chain C
2hvd chain A
2hvd chain B
2hvd chain C
2hve chain A
2hve chain B
2hve chain C
3l7u chain A
3l7u chain B
3l7u chain C
4eno chain A
4eno chain B
5ui4 chain A
5ui4 chain B
5ui4 chain C
5ui4 chain D
5ui4 chain E
5ui4 chain F
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S120 GRNIIHGS DSVESAE 9 396 39 - 4 4 - - 99 - 9 8 48 46 13 12 47 12 10 4 39 2 S122 NIIHGSDS VESAEKE 5 128 35 - - - - - 26 - 17 9 4 4 - - 25 8 - - - - S125 HGSDSVES AEKEIGL 4 94 8 - - - - - 36 - - - - - 13 11 22 4 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S120 GRNIIHGS DSVESAE 4.3e-3 - - - - - 7.3e-4 - 0.51 - - S122 NIIHGSDS VESAEKE - - - - - - - - - - - S125 HGSDSVES AEKEIGL - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S120
S122
S125
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S120 S122 S125 protein RNA SCNV methylation CCRCC S120 S122 S125 protein RNA SCNV methylation COAD S120 S122 S125 protein RNA SCNV methylation GBM S120 S122 S125 protein RNA SCNV methylation HNSCC S120 S122 S125 protein RNA SCNV methylation LSCC S120 S122 S125 protein RNA SCNV methylation LUAD S120 S122 S125 protein RNA SCNV methylation OV S120 S122 S125 protein RNA SCNV methylation PDAC S120 S122 S125 protein RNA SCNV methylation UCEC S120 S122 S125 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S120
S122
S125
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S120
S122
S125
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.