Protein: ENSP00000377015

PICALM:: phosphatidylinositol binding clathrin assembly protein

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S16	RITAAQHSVTGSAVS	10	1087	33	-	103	80	73	70	63	-	70	39	88	80	27	23	83	19	105	44	73	14
S20	AQHSVTGSAVSKTVC	1	5	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	3	2	-	-
T301	TAASRATTLSNAVSS	5	216	30	-	4	4	13	14	-	-	-	-	44	40	35	32	-	-	-	-	-	-
S303	ASRATTLSNAVSSLA	10	816	37	-	57	37	47	49	54	-	85	48	53	47	54	48	23	3	97	32	34	11
S307	TTLSNAVSSLASTGL	4	159	7	-	-	-	49	50	-	-	-	-	5	4	-	-	-	-	32	12	-	-
S308	TLSNAVSSLASTGLS	7	570	61	-	61	57	-	-	-	-	13	6	69	63	97	88	-	-	35	12	5	3
S311	NAVSSLASTGLSLTK	8	620	62	-	41	39	6	3	-	-	55	34	63	58	83	76	-	-	66	27	5	2
T312	AVSSLASTGLSLTKV	1	8	8	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S315	SLASTGLSLTKVDER	10	892	24	-	33	29	79	82	46	-	91	52	74	67	67	60	28	5	54	25	65	11
S353	LAKKPHTSLTTAASP	4	79	-	-	-	-	-	-	-	-	6	4	5	5	9	9	-	-	29	12	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S16	RITAAQHSVTGSAVS	3.8e-11	-	-0.013	0.16	-	1.3e-5	2.9e-3	3.2e-9	0.56	5.6e-10	-0.8
S20	AQHSVTGSAVSKTVC	-	-	-	-	-	-	-	-	-	-	-
T301	TAASRATTLSNAVSS	-2.3e-21	-	-	-	-	-	-2.1e-14	-7.5e-9	-	-	-
S303	ASRATTLSNAVSSLA	0.027	-	-2.7e-8	2.5e-6	-	0.33	-0.42	0.59	-	6.9e-9	0.82
S307	TTLSNAVSSLASTGL	2.6e-7	-	-	8.4e-3	-	-	-	-	-	3.4e-6	-
S308	TLSNAVSSLASTGLS	-1.7e-8	-	-2.1e-10	-	-	-	-1.2e-4	-2.6e-7	-	4.8e-5	-
S311	NAVSSLASTGLSLTK	-1.2e-7	-	-1.8e-9	-	-	-0.31	-8.6e-7	-1.3e-5	-	7.7e-6	-
T312	AVSSLASTGLSLTKV	-	-	-	-	-	-	-	-	-	-	-
S315	SLASTGLSLTKVDER	2.5e-20	-	0.18	0.041	-	0.005	3.8e-5	4.5e-10	-	8.0e-6	6.1e-4
S353	LAKKPHTSLTTAASP	9.8e-4	-	-	-	-	-	-	-	-	9.8e-4	-

Showing 1 to 10 of 24 rows

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000377015Gene: PICALM

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000377015
Gene: PICALM