PTPRZ1: protein tyrosine phosphatase receptor type Z1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3jxf chain A
3jxf chain B
3s97 chain A
3s97 chain B
5awx chain A
5h08 chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S449 IVNPGRDS ATNQIRK 1 98 - - - - - - 98 - - - - - - - - - - - - - S656 EGNVWFPS STDITAQ 1 9 - - - - - - 9 - - - - - - - - - - - - - S1333 LINKLIHS DEILTST 1 90 - - - - - - 90 - - - - - - - - - - - - - S1400 LFPSKATS ELSHSAK 1 73 - - - - - - 73 - - - - - - - - - - - - - S1405 ATSELSHS AKSDAGL 1 18 - - - - - - 18 - - - - - - - - - - - - - T1421 GGGEDGDT DDDGDDD 1 60 - - - - - - 60 - - - - - - - - - - - - - S1434 DDDDDRGS DGLSIHK 1 35 - - - - - - 35 - - - - - - - - - - - - - S1444 LSIHKCMS CSSYRES 1 19 - - - - - - 19 - - - - - - - - - - - - - S1446 IHKCMSCS SYRESQE 1 81 - - - - - - 81 - - - - - - - - - - - - - S1447 HKCMSCSS YRESQEK 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S449 IVNPGRDS ATNQIRK - - - - - - - - - - - S656 EGNVWFPS STDITAQ - - - - - - - - - - - S1333 LINKLIHS DEILTST - - - - - - - - - - - S1400 LFPSKATS ELSHSAK - - - - - - - - - - - S1405 ATSELSHS AKSDAGL - - - - - - - - - - - T1421 GGGEDGDT DDDGDDD - - - - - - - - - - - S1434 DDDDDRGS DGLSIHK - - - - - - - - - - - S1444 LSIHKCMS CSSYRES - - - - - - - - - - - S1446 IHKCMSCS SYRESQE - - - - - - - - - - - S1447 HKCMSCSS YRESQEK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S449
S656
S1333
S1400
S1405
T1421
S1434
S1444
S1446
S1447
S1451
S1528
S1534
S1676
S1683
T1684
T1687
S1714
S1715
S1733
S1765
Y1782
Y1787
S2033
T2054
S2055
S2056
Y2179
S2196
S2248
S2297
S2310
S2313
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation CCRCC S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation COAD S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation GBM S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation HNSCC S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation LSCC S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation LUAD S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation OV S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation PDAC S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation UCEC S449 S656 S1333 S1400 S1405 T1421 S1434 S1444 S1446 S1447 S1451 S1528 S1534 S1676 S1683 T1684 T1687 S1714 S1715 S1733 S1765 Y1782 Y1787 S2033 T2054 S2055 S2056 Y2179 S2196 S2248 S2297 S2310 S2313 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S449
S656
S1333
S1400
S1405
T1421
S1434
S1444
S1446
S1447
S1451
S1528
S1534
S1676
S1683
T1684
T1687
S1714
S1715
S1733
S1765
Y1782
Y1787
S2033
T2054
S2055
S2056
Y2179
S2196
S2248
S2297
S2310
S2313
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S449
S656
S1333
S1400
S1405
T1421
S1434
S1444
S1446
S1447
S1451
S1528
S1534
S1676
S1683
T1684
T1687
S1714
S1715
S1733
S1765
Y1782
Y1787
S2033
T2054
S2055
S2056
Y2179
S2196
S2248
S2297
S2310
S2313
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.