G6PD: glucose-6-phosphate dehydrogenase
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1qki chain A
1qki chain B
1qki chain C
1qki chain D
1qki chain E
1qki chain F
1qki chain G
1qki chain H
2bh9 chain A
2bhl chain A
2bhl chain B
5ukw chain A
6e07 chain B
6e07 chain C
6e07 chain F
6e07 chain L
6e07 chain N
6e07 chain Q
6e07 chain T
6e07 chain W
6e08 chain L
6jyu chain A
6va0 chain A
6va7 chain A
6va8 chain A
6va9 chain A
6vaq chain A
7seh chain A
7seh chain B
7sei chain A
7snf chain A
7snf chain B
7sng chain A
7sng chain B
7sng chain C
7sng chain D
7snh chain A
7snh chain B
7snh chain C
7snh chain D
7sni chain A
7sni chain B
7sni chain C
7sni chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S84 VADIRKQS EPFFKAT 2 26 9 - - - - - 17 - - - - - - - - - - - - - Y401 VQPNEAVY TKMMTKK 10 1189 96 - 88 65 11 16 81 - 108 62 98 90 110 101 7 2 100 41 95 18 Y503 MKRVGFQY EGTYKWV 6 288 70 - - - - - 18 - - - 59 55 33 28 - - 14 5 6 - Y507 GFQYEGTY KWVNPHK 2 16 6 - - - - - - - - - 5 5 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S84 VADIRKQS EPFFKAT - - - - - - - - - - - Y401 VQPNEAVY TKMMTKK 3.3e-9 - 3.3e-12 - - 1.2e-5 -0.85 -0.034 - 8.8e-5 0.12 Y503 MKRVGFQY EGTYKWV -0.22 - - - - - -0.76 -0.16 - - - Y507 GFQYEGTY KWVNPHK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S84
Y401
Y503
Y507
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S84 Y401 Y503 Y507 protein RNA SCNV methylation CCRCC S84 Y401 Y503 Y507 protein RNA SCNV methylation COAD S84 Y401 Y503 Y507 protein RNA SCNV methylation GBM S84 Y401 Y503 Y507 protein RNA SCNV methylation HNSCC S84 Y401 Y503 Y507 protein RNA SCNV methylation LSCC S84 Y401 Y503 Y507 protein RNA SCNV methylation LUAD S84 Y401 Y503 Y507 protein RNA SCNV methylation OV S84 Y401 Y503 Y507 protein RNA SCNV methylation PDAC S84 Y401 Y503 Y507 protein RNA SCNV methylation UCEC S84 Y401 Y503 Y507 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S84
Y401
Y503
Y507
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S84
Y401
Y503
Y507
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.