Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3ifq chain A
3ifq chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y20 VTEWQQTY TYDSGIH 1 45 - - - - - - - - 29 16 - - - - - - - - - - Y22 EWQQTYTY DSGIHSG 1 10 - - - - - - - - 6 4 - - - - - - - - - - S24 QQTYTYDS GIHSGAN 5 286 9 - - - 5 4 - - 71 44 64 56 - - - - - - 26 7 S28 TYDSGIHS GANTCVP 6 228 15 - - - 9 9 - - 95 56 15 11 - - - - 4 2 12 - T32 GIHSGANT CVPSVSS 6 78 - - 4 4 5 4 - - 12 7 10 9 9 7 - - - - 5 2 S36 GANTCVPS VSSKGIM 2 57 - - - - - - - - 6 4 25 22 - - - - - - - - S38 NTCVPSVS SKGIMEE 4 38 - - - - - - - - 5 4 9 6 5 4 - - 4 1 - - S39 TCVPSVSS KGIMEED 1 10 - - - - - - - - 6 4 - - - - - - - - - - T54 EACGRQYT LKKTTTY 1 8 8 - - - - - - - - - - - - - - - - - - - S68 YTQGVPPS QGDLEYQ 2 255 - - - - - - - - 98 54 54 49 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y20 VTEWQQTY TYDSGIH -4.5e-4 - - - - -4.5e-4 - - - - - Y22 EWQQTYTY DSGIHSG - - - - - - - - - - - S24 QQTYTYDS GIHSGAN 6e-15 - - - - 0.02 3.2e-18 - - - - S28 TYDSGIHS GANTCVP 0.13 - - - - 0.13 - - - - - T32 GIHSGANT CVPSVSS - - - - - - - - - - - S36 GANTCVPS VSSKGIM 2.6e-7 - - - - - 2.6e-7 - - - - S38 NTCVPSVS SKGIMEE - - - - - - - - - - - S39 TCVPSVSS KGIMEED - - - - - - - - - - - T54 EACGRQYT LKKTTTY - - - - - - - - - - - S68 YTQGVPPS QGDLEYQ 1.4e-8 - - - - 0.039 2.4e-9 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y20
Y22
S24
S28
T32
S36
S38
S39
T54
S68
Y74
S94
S98
S99
S120
S125
S170
S182
S365
S401
T427
S433
Y480
Y550
Y594
S596
Y644
S665
T669
S671
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation CCRCC Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation COAD Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation GBM Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation HNSCC Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation LSCC Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation LUAD Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation OV Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation PDAC Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation UCEC Y20 Y22 S24 S28 T32 S36 S38 S39 T54 S68 Y74 S94 S98 S99 S120 S125 S170 S182 S365 S401 T427 S433 Y480 Y550 Y594 S596 Y644 S665 T669 S671 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y20
Y22
S24
S28
T32
S36
S38
S39
T54
S68
Y74
S94
S98
S99
S120
S125
S170
S182
S365
S401
T427
S433
Y480
Y550
Y594
S596
Y644
S665
T669
S671
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y20
Y22
S24
S28
T32
S36
S38
S39
T54
S68
Y74
S94
S98
S99
S120
S125
S170
S182
S365
S401
T427
S433
Y480
Y550
Y594
S596
Y644
S665
T669
S671
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.