CBLB:
Cbl proto-oncogene B

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S476KCTDRQNSPVTSPGS834217-54141318---44413935--1167718
T479DRQNSPVTSPGSSPL46018-88----52109--------
S480RQNSPVTSPGSSPLA1074580-4229333936-33218981585322541174818
S483SPVTSPGSSPLAQRR61329-------11710944--3215283
S484PVTSPGSSPLAQRRK953123---606545-221415151312491074296718
S521IQKGIVRSPCGSPTG982830-2020708299-633594854944--46205318
S525IVRSPCGSPTGSPKS984596-10380494199-4828151210596--3111292
T527RSPCGSPTGSPKSSP7314--7568232217-38191514----968-
S529PCGSPTGSPKSSPCM8316--43282681-171010854--49203516
S533PTGSPKSSPCMVRKQ1078514-13126372-341898908780771637159518
Showing 1 to 10 of 25 rows
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S476KCTDRQNSPVTSPGS2.1e-7-----1.4e-60.91--4.9e-5
T479DRQNSPVTSPGSSPL-----------
S480RQNSPVTSPGSSPLA-6.4e-3--0.0060.4-0.05-2.4e-3-1.2e-3-0.025-1.2e-3
S483SPVTSPGSSPLAQRR7.0e-4--------6.9e-4-
S484PVTSPGSSPLAQRRK1.6e-15--5.5e-12-2.3e-6---0.81.9e-60.09
S521IQKGIVRSPCGSPTG1.2e-8-0.140.025-5.5e-80.0274.9e-3--0.270.044
S525IVRSPCGSPTGSPKS1.4e-21-1.8e-81.4e-6-8.8e-8-9.9e-13--0.11-
T527RSPCGSPTGSPKSSP1.5e-17-1.1e-110.029-6.9e-9-----
S529PCGSPTGSPKSSPCM4.6e-4--1.8e-3-----0.130.15
S533PTGSPKSSPCMVRKQ4.6e-16----1.4e-125.2e-91.3e-5-0.56-0.62.0e-4
Showing 1 to 10 of 25 rows
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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationCCRCCS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationCOADS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationGBMS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationHNSCCS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationLSCCS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationLUADS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationOVS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationPDACS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylationUCECS476T479S480S483S484S521S525T527S529S533S580S614S634Y665S672T678S693Y709S794S800Y802S847S886Y889S977proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.