Protein: ENSP00000377807
Gene: FAM122A

LinkedOmicsKB © 2022-2023 Zhang Lab

FAM122A:
PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T16DLELPPGTGGSPAEG384--129------20181312------
S19LPPGTGGSPAEGGGS61086-77----127--1213--1171313
S35GGGGLRRSNSAPLIH91608-446355---5589203113115
S37GGLRRSNSAPLIHGL1098746-1918929699-8450353429288319100429518
S45APLIHGLSDTSPVFQ4868-------63553128------
T47LIHGLSDTSPVFQAE82238-131012636-11735311312----29-
S48IHGLSDTSPVFQAEA232------18-----------122
S62APSARRNSTTFPSRH1093567-5039555399-75426559554783193211777
S76HGLLLPASPVRMHSS101553122-103809710099-10862108991101018319105449518
T109VHEREVQTAMQISHS19------------45------
Showing 1 to 10 of 27 rows
102550
rows per page

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T16DLELPPGTGGSPAEG-0.15------0.15----
S19LPPGTGGSPAEGGGS-----------
S35GGGGLRRSNSAPLIH-----------
S37GGLRRSNSAPLIHGL-0.11---0.087--0.023-0.86-2.7e-40.612.8e-6-0.091
S45APLIHGLSDTSPVFQ-0.072-------0.072---
T47LIHGLSDTSPVFQAE-1.0e-4------1.0e-4----
S48IHGLSDTSPVFQAEA-----------
S62APSARRNSTTFPSRH-5.9e-4-0.026-7.6e-4--0.17-3.4e-8-0.0610.50.9-
S76HGLLLPASPVRMHSS-6.4e-9-0.24-7.2e-3--0.011-2e-9-6.4e-9-0.410.27-0.4
T109VHEREVQTAMQISHS-----------
Showing 1 to 10 of 27 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationCCRCCT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationCOADT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationGBMT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationHNSCCT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationLSCCT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationLUADT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationOVT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationPDACT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylationUCECT16S19S35S37S45T47S48S62S76T109S143S147T149S158S160S167S173S177S187S189S197S257S267S270S276S285S286proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.