GTF2F1: general transcription factor IIF subunit 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1f3u chain B
1f3u chain D
1f3u chain F
1f3u chain H
1i27 chain A
1j2x chain A
1nha chain A
1onv chain A
2k7l chain A
5iy6 chain S
5iy7 chain S
5iy8 chain S
5iy9 chain S
5iya chain S
5iyb chain S
5iyc chain S
5iyd chain S
6o9l chain S
7edx chain S
7eg7 chain S
7eg8 chain S
7eg9 chain S
7ega chain S
7egb chain S
7egc chain S
7ena chain FA
7enc chain FA
7lbm chain S
7nvr chain Q
7nvs chain Q
7nvt chain Q
7nvu chain Q
7nvy chain Q
7nvz chain Q
7nw0 chain Q
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T154 TPLARHRT LTAEEAE 9 547 8 - 36 25 19 17 99 - 19 9 53 47 64 56 - - 48 19 23 5 T156 LARHRTLT AEEAEEE 10 1198 98 - 66 46 30 33 81 - 96 55 93 85 102 93 75 18 80 34 95 18 S217 LEDDLEMS SDASDAS 8 564 96 - 24 24 22 13 72 - - - 98 84 13 12 - - 70 30 6 - S218 EDDLEMSS DASDASG 9 1129 96 - 92 69 22 14 88 - 102 58 103 89 98 86 - - 90 39 67 16 S221 LEMSSDAS DASGEEG 9 267 14 - 87 65 4 5 18 - 11 5 5 5 5 4 - - 9 3 24 3 S224 SSDASDAS GEEGGRV 9 319 21 - 13 11 4 5 46 - 6 3 59 46 25 20 - - 11 4 38 7 S305 PKGVDEQS DSSEESE 6 154 - - - - 6 11 9 - 6 3 24 20 4 4 - - - - 49 18 S307 GVDEQSDS SEESEEE 9 810 54 - 72 67 32 29 8 - 90 53 103 86 90 78 - - 28 11 7 2 S308 VDEQSDSS EESEEEK 9 921 6 - 72 67 32 29 90 - 90 53 103 86 90 78 - - 25 10 72 18 S311 QSDSSEES EEEKPPE 9 259 17 - 22 22 7 2 27 - 28 14 20 18 17 15 - - 13 4 33 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T154 TPLARHRT LTAEEAE 8.6e-3 - -0.67 - - - 2.3e-4 2.2e-7 - -1.5e-3 - T156 LARHRTLT AEEAEEE -2.2e-31 - 0.059 -1.4e-4 - -2.5e-9 -6.2e-12 -5.7e-10 -2.8e-5 -8.1e-5 -1.0e-4 S217 LEDDLEMS SDASDAS 2.6e-7 - 0.86 0.026 - - 1.2e-16 - - -0.7 - S218 EDDLEMSS DASDASG 3.2e-19 - -8.3e-7 0.012 - 2.6e-14 2e-16 1.8e-15 - 0.5 0.098 S221 LEMSSDAS DASGEEG -2.6e-5 - -2.6e-5 - - - - - - - - S224 SSDASDAS GEEGGRV 4e-9 - - - - - 7.7e-7 7.3e-4 - - - S305 PKGVDEQS DSSEESE 5e-15 - - - - - 7.8e-10 - - - 8.7e-7 S307 GVDEQSDS SEESEEE 5.4e-21 - -1.5e-16 4.3e-11 - 7.9e-10 7e-24 9.4e-17 - 0.91 - S308 VDEQSDSS EESEEEK 1.1e-26 - -9.1e-16 4.3e-11 - 6.5e-10 7.8e-24 1.6e-16 - 0.59 2.4e-6 S311 QSDSSEES EEEKPPE 0.004 - -0.35 - - 0.55 9.5e-8 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T154
T156
S217
S218
S221
S224
S305
S307
S308
S311
T331
S341
S342
S347
S348
S377
S380
S381
S385
T389
T427
S431
S433
S436
T437
S442
T445
T446
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation CCRCC T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation COAD T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation GBM T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation HNSCC T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation LSCC T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation LUAD T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation OV T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation PDAC T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation UCEC T154 T156 S217 S218 S221 S224 S305 S307 S308 S311 T331 S341 S342 S347 S348 S377 S380 S381 S385 T389 T427 S431 S433 S436 T437 S442 T445 T446 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T154
T156
S217
S218
S221
S224
S305
S307
S308
S311
T331
S341
S342
S347
S348
S377
S380
S381
S385
T389
T427
S431
S433
S436
T437
S442
T445
T446
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T154
T156
S217
S218
S221
S224
S305
S307
S308
S311
T331
S341
S342
S347
S348
S377
S380
S381
S385
T389
T427
S431
S433
S436
T437
S442
T445
T446
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.