Protein: ENSP00000378026
Gene: AKAP13

LinkedOmicsKB © 2022-2023 Zhang Lab

AKAP13:
A-kinase anchoring protein 13

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S131PPSGDVNSLDKKLVL330------9---------52122
S345STQCCPGSPVAQTES9423--2422493987-1891091087229117316
T350PGSPVAQTESPCDLS6199--1212--14-4725----71491769
S352SPVAQTESPCDLSSI220----------------32105
S391EPAPIVDSGTVSDQD15----------------32--
S395IVDSGTVSDQDSCLQ103439-33206318-6238252287712911404
S399GTVSDQDSCLQSLPD921523-2020--18-1810151326257173-9
S403DQDSCLQSLPDCGVK832630-8799--221444413532--219405
S438GMPTDQESLSSGDAV481--54------151588----242
S503NVLQGGESTKERFEN4191--1310----2512--6660--32--
Showing 1 to 10 of 136 rows
102550100
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S131PPSGDVNSLDKKLVL-----------
S345STQCCPGSPVAQTES0.084--0.080.21-----0.010.16
T350PGSPVAQTESPCDLS3.8e-3----0.53---5.4e-4-
S352SPVAQTESPCDLSSI-----------
S391EPAPIVDSGTVSDQD-----------
S395IVDSGTVSDQDSCLQ-0.015--0.95---0.42-1.9e-3---0.37-
S399GTVSDQDSCLQSLPD-0.36--0.66-----0.39---
S403DQDSCLQSLPDCGVK-0.084----0.67-2.2e-3-0.72---
S438GMPTDQESLSSGDAV-----------
S503NVLQGGESTKERFEN-0.25----0.035--1.9e-4---
Showing 1 to 10 of 136 rows
102550100
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

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

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.