BAD:
BCL2 associated agonist of cell death

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S25AERGLGPSPAGDGPS10126481-7856432981-10358108991101014612103439518
S32SPAGDGPSGSGKHHR717230-168108--11715132320--83--
S34AGDGPSGSGKHHRQA6198------81---5554225186407
S71AGAVEIRSRHSSYPA118------18-------------
S75EIRSRHSSYPAGTED94598-1212544563-541917--62153918806
Y76IRSRHSSYPAGTEDD1052730-2018374362-16122424423628739165716
T80HSSYPAGTEDDEGMG727114-1212--9-291840375043----7-
S91EGMGEEPSPFRGRSR227------19-------71----
S99PFRGRSRSAPPNLWA101553122-103809710099-10862108991101018319105449518
S118GRELRRMSDEFVDSF101553122-103809710099-10862108991101018319105449518
Showing 1 to 10 of 16 rows
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S25AERGLGPSPAGDGPS-1.3e-15--0.015-1.9e-3--1.1e-4-4.8e-8-5.5e-5-0.59-8e-141.7e-5
S32SPAGDGPSGSGKHHR-0.11-------0.11---
S34AGDGPSGSGKHHRQA-----------
S71AGAVEIRSRHSSYPA-----------
S75EIRSRHSSYPAGTED0.027---0.79----0.0480.033-
Y76IRSRHSSYPAGTEDD-0.34--0.99-5.7e-3---0.320.15-0.083-0.084
T80HSSYPAGTEDDEGMG0.36----0.036-5.7e-30.024---
S91EGMGEEPSPFRGRSR-----------
S99PFRGRSRSAPPNLWA0.003--2.7e-4-7.6e-4-4.1e-80.370.640.512.3e-80.02
S118GRELRRMSDEFVDSF-0.62--1.3e-7-1.2e-9-2.1e-75.7e-49.8e-6-0.62-0.0750.046
Showing 1 to 10 of 16 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationCCRCCS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationCOADS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationGBMS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationHNSCCS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationLSCCS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationLUADS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationOVS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationPDACS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylationUCECS25S32S34S71S75Y76T80S91S99S118S124S134S144S145S146S163proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.