GRM2: glutamate metabotropic receptor 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4xaq chain A
4xaq chain B
4xas chain A
4xas chain B
5cni chain A
5cni chain B
5cnj chain A
5cnj chain B
5kzn chain A
5kzq chain A
7e9g chain R
7e9g chain S
7epa chain A
7epa chain B
7epb chain A
7epb chain B
7epd chain A
7epe chain A
7epf chain A
7mtq chain A
7mtq chain B
7mtr chain A
7mtr chain B
7mts chain A
7mts chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S837 APTSRFGS AAARASS 1 78 - - - - - - 78 - - - - - - - - - - - - - S843 GSAAARAS SSLGQGS 1 18 - - - - - - 18 - - - - - - - - - - - - - S870 EVVDSTTS SL_____ 1 9 - - - - - - 9 - - - - - - - - - - - - - S871 VVDSTTSS L______ 1 26 - - - - - - 26 - - - - - - - - - - - - -
Tumor and normal comparison
Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S837 APTSRFGS AAARASS - - - - - - - - - - - S843 GSAAARAS SSLGQGS - - - - - - - - - - - S870 EVVDSTTS SL_____ - - - - - - - - - - - S871 VVDSTTSS L______ - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
Loading, please wait
all sites
S837
S843
S870
S871
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S837 S843 S870 S871 protein RNA SCNV methylation CCRCC S837 S843 S870 S871 protein RNA SCNV methylation COAD S837 S843 S870 S871 protein RNA SCNV methylation GBM S837 S843 S870 S871 protein RNA SCNV methylation HNSCC S837 S843 S870 S871 protein RNA SCNV methylation LSCC S837 S843 S870 S871 protein RNA SCNV methylation LUAD S837 S843 S870 S871 protein RNA SCNV methylation OV S837 S843 S870 S871 protein RNA SCNV methylation PDAC S837 S843 S870 S871 protein RNA SCNV methylation UCEC S837 S843 S870 S871 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S837
S843
S870
S871
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S837
S843
S870
S871
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.