Protein: ENSP00000378557
Gene: DAAM1

LinkedOmicsKB © 2022-2023 Zhang Lab

DAAM1:
dishevelled associated activator of morphogenesis 1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S602GLALKKKSIPQPTNA6118--44--9-1161514--71--3314
S1027MRKAKENSEESGEFD7264----81072-392514132824--321214
S1030AKENSEESGEFDDLV590--------54191614124---124
T1061KRNRKRITNQMTDSS220--------------81--92
S1067ITNQMTDSSRERPIT5132----314018---10944124----
Showing 1 to 5 of 5 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S602GLALKKKSIPQPTNA-0.061----------0.061
S1027MRKAKENSEESGEFD0.59-----0.35-0.09---
S1030AKENSEESGEFDDLV-----------
T1061KRNRKRITNQMTDSS-----------
S1067ITNQMTDSSRERPIT-7.8e-3---7.8e-3-------
Showing 1 to 5 of 5 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PATH-NP_EGFR1_PATHWAYS10271.4e-3---0.0023.8e-30.54-0.47--0.2
HALLMARK_HEME_METABOLISMS10272.7e-3---0.750.0340.320.033--0.26
KINASE-PSP_PKACA/PRKACAS10270.003---0.810.0290.490.066--0.094
PERT-PSP_SII_ANGIOTENSIN_2S10273.2e-3---3.9e-3-----0.2
KINASE-PSP_MAPKAPK2S10273.6e-3---0.510.490.17---0.002
HALLMARK_INTERFERON_ALPHA_RESPONSES10277.7e-3---0.0050.330.41-1--0.18
SBS4 (smoking)S10678.9e-3-----8.9e-3----
PROGENy: WNTS10300.012-----0.0270.062--0.8
KINASE-PSP_AurB/AURKBS10270.015---0.980.280.20.15--0.1
PERT-P100-PRM_VORINOSTATS10670.015---0.015------
Showing 1 to 10 of 1290 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS602S1027S1030T1061S1067proteinRNASCNVmethylationCCRCCS602S1027S1030T1061S1067proteinRNASCNVmethylationCOADS602S1027S1030T1061S1067proteinRNASCNVmethylationGBMS602S1027S1030T1061S1067proteinRNASCNVmethylationHNSCCS602S1027S1030T1061S1067proteinRNASCNVmethylationLSCCS602S1027S1030T1061S1067proteinRNASCNVmethylationLUADS602S1027S1030T1061S1067proteinRNASCNVmethylationOVS602S1027S1030T1061S1067proteinRNASCNVmethylationPDACS602S1027S1030T1061S1067proteinRNASCNVmethylationUCECS602S1027S1030T1061S1067proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.