Protein: ENSP00000378577
Gene: CLDN3

LinkedOmicsKB © 2022-2023 Zhang Lab

CLDN3:
claudin 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

Loading, please wait
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T194REKKYTATKVVYSAP19----45--------------
Y198YTATKVVYSAPRSTG970441-24229296--241310105951551272317616
S199TATKVVYSAPRSTGP81477-2120810----108131216241132
S203VVYSAPRSTGPGASL942417-886362--11614134469144018649
T204VYSAPRSTGPGASLG72419-382663------22191323217459
S209RSTGPGASLGTGYDR91211104-81609089--753993859183711487369518
T212GPGASLGTGYDRKDY524832-37183743------2320----317
Y214GASLGTGYDRKDYV_6829---612------541431784-
Y219TGYDRKDYV______199-------------------
Showing 1 to 9 of 9 rows

Tumor and normal comparison

Loading, please wait
Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T194REKKYTATKVVYSAP-----------
Y198YTATKVVYSAPRSTG2.8e-4--8.9e-108.7e-17-0.63-4e-166.1e-6-9.5e-110.46
S199TATKVVYSAPRSTGP-1.0e-6--1.0e-6--------
S203VVYSAPRSTGPGASL-0.047--4.6e-3----0.9-1.5e-10-
T204VYSAPRSTGPGASLG-3.3e-4--8.5e-6----9.0e-5--1.3e-8-
S209RSTGPGASLGTGYDR0.085--1e-80.56--0.89-0.133.1e-221.3e-4-1.0e-50.01
T212GPGASLGTGYDRKDY0.11--1.2e-60.077---5.7e-9---
Y214GASLGTGYDRKDYV_-----------
Y219TGYDRKDYV______-----------
Showing 1 to 9 of 9 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

Loading, please wait
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationCCRCCT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationCOADT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationGBMT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationHNSCCT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationLSCCT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationLUADT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationOVT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationPDACT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylationUCECT194Y198S199S203T204S209T212Y214Y219proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

Loading, please wait
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

Loading, please wait
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.