DIDO1: death inducer-obliterator 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2m3h chain A
4l7x chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S60 PQQQLGLS LRRSGRQ 6 161 8 - 58 46 - - - - - - 10 9 9 8 7 2 - - 4 - S88 ARRRGRRS MPVSLED 1 18 - - - - - - - - - - - - - - - - - - 7 11 S92 GRRSMPVS LEDSGEP 1 8 - - 4 4 - - - - - - - - - - - - - - - - S96 MPVSLEDS GEPTSCP 1 8 - - 4 4 - - - - - - - - - - - - - - - - T100 LEDSGEPT SCPATDA 3 39 25 - - - - - - - - - 5 1 4 4 - - - - - - S101 EDSGEPTS CPATDAE 4 47 25 - 4 4 - - - - - - 5 1 4 4 - - - - - - T105 EPTSCPAT DAETASE 4 39 17 - 4 2 - - - - - - - - 4 4 - - - - 5 3 T109 CPATDAET ASEGSVE 2 17 8 - - - - - - - - - - - 4 5 - - - - - - S111 ATDAETAS EGSVESA 8 258 6 - - - 11 7 28 - - - 44 35 12 11 5 - 5 2 74 18 S114 AETASEGS VESASET 6 106 - - - - 11 7 34 - - - - - 4 4 5 - 5 2 28 6
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S60 PQQQLGLS LRRSGRQ -0.33 - -0.33 - - - - - - - - S88 ARRRGRRS MPVSLED - - - - - - - - - - - S92 GRRSMPVS LEDSGEP - - - - - - - - - - - S96 MPVSLEDS GEPTSCP - - - - - - - - - - - T100 LEDSGEPT SCPATDA - - - - - - - - - - - S101 EDSGEPTS CPATDAE - - - - - - - - - - - T105 EPTSCPAT DAETASE - - - - - - - - - - - T109 CPATDAET ASEGSVE - - - - - - - - - - - S111 ATDAETAS EGSVESA 2.7e-4 - - - - - 4.4e-3 - - - 0.021 S114 AETASEGS VESASET - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S60
S88
S92
S96
T100
S101
T105
T109
S111
S114
S117
S123
S127
S138
T151
S152
S154
S156
T208
T320
T328
S330
S352
T502
S523
S571
S572
S650
S805
S809
S862
S898
S912
S947
S988
S1019
S1030
S1034
T1035
S1036
S1038
S1040
S1254
T1255
T1256
S1260
S1285
T1310
S1312
S1456
T1469
S1617
S1621
T1662
S1713
S1714
T1719
T1733
S1827
S2124
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation CCRCC S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation COAD S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation GBM S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation HNSCC S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation LSCC S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation LUAD S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation OV S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation PDAC S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation UCEC S60 S88 S92 S96 T100 S101 T105 T109 S111 S114 S117 S123 S127 S138 T151 S152 S154 S156 T208 T320 T328 S330 S352 T502 S523 S571 S572 S650 S805 S809 S862 S898 S912 S947 S988 S1019 S1030 S1034 T1035 S1036 S1038 S1040 S1254 T1255 T1256 S1260 S1285 T1310 S1312 S1456 T1469 S1617 S1621 T1662 S1713 S1714 T1719 T1733 S1827 S2124 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S60
S88
S92
S96
T100
S101
T105
T109
S111
S114
S117
S123
S127
S138
T151
S152
S154
S156
T208
T320
T328
S330
S352
T502
S523
S571
S572
S650
S805
S809
S862
S898
S912
S947
S988
S1019
S1030
S1034
T1035
S1036
S1038
S1040
S1254
T1255
T1256
S1260
S1285
T1310
S1312
S1456
T1469
S1617
S1621
T1662
S1713
S1714
T1719
T1733
S1827
S2124
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S60
S88
S92
S96
T100
S101
T105
T109
S111
S114
S117
S123
S127
S138
T151
S152
S154
S156
T208
T320
T328
S330
S352
T502
S523
S571
S572
S650
S805
S809
S862
S898
S912
S947
S988
S1019
S1030
S1034
T1035
S1036
S1038
S1040
S1254
T1255
T1256
S1260
S1285
T1310
S1312
S1456
T1469
S1617
S1621
T1662
S1713
S1714
T1719
T1733
S1827
S2124
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.