Protein: ENSP00000378856
Gene: LGALS9

LinkedOmicsKB © 2022-2023 Zhang Lab

LGALS9:
galectin 9

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S286RNTQIDNSWGSEERS351----------551816----52
S289QIDNSWGSEERSLPR115------------87------
S293SWGSEERSLPRKMPF233----------------84183
Showing 1 to 3 of 3 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S286RNTQIDNSWGSEERS-----------
S289QIDNSWGSEERSLPR-----------
S293SWGSEERSLPRKMPF-----------
Showing 1 to 3 of 3 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Clinical: BMIS2935.5e-3---------5.5e-3
HALLMARK_PEROXISOMES2930.017---------0.017
xcell: Granulocyte-monocyte progenitorS2860.024------0.024---
HALLMARK_BILE_ACID_METABOLISMS2930.026---------0.026
HALLMARK_APOPTOSISS2860.038------0.038---
PROGENy: TrailS2930.041---------0.041
HALLMARK_APICAL_SURFACES2860.048------0.048---
KINASE-PSP_JNK1/MAPK8S2930.048---------0.048
HALLMARK_P53_PATHWAYS2860.059------0.059---
HALLMARK_ESTROGEN_RESPONSE_EARLYS2930.061---------0.061
Showing 1 to 10 of 774 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS286S289S293proteinRNASCNVmethylationCCRCCS286S289S293proteinRNASCNVmethylationCOADS286S289S293proteinRNASCNVmethylationGBMS286S289S293proteinRNASCNVmethylationHNSCCS286S289S293proteinRNASCNVmethylationLSCCS286S289S293proteinRNASCNVmethylationLUADS286S289S293proteinRNASCNVmethylationOVS286S289S293proteinRNASCNVmethylationPDACS286S289S293proteinRNASCNVmethylationUCECS286S289S293proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
MTMR2S286-0.001-------0.001---
PTP4A2S293-0.002----------0.002
PPM1DS286-7.5e-3-------7.5e-3---
PTPN21S293-0.011----------0.011
PTPRGS293-0.023----------0.023
DUSP22S286-0.028-------0.028---
PPP1CCS293-0.029----------0.029
INPP5AS286-0.034-------0.034---
DUSP12S293-0.041----------0.041
NT5C3BS293-0.043----------0.043
Showing 1 to 10 of 720 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.