CAMK2B: calcium/calmodulin dependent protein kinase II beta
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3bhh chain A
3bhh chain B
3bhh chain C
3bhh chain D
7urw chain A
7urw chain B
7urw chain C
7urw chain D
7urw chain E
7urw chain F
7urw chain G
7ury chain A
7ury chain B
7ury chain C
7ury chain D
7ury chain E
7ury chain F
7ury chain G
7urz chain A
7urz chain B
7urz chain C
7urz chain G
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T287 SMMHRQET VECLKKF 7 668 - - 90 68 - - 99 - 100 59 28 25 23 20 - - 99 42 13 2 T321 FSVGRQTT APATMST 2 117 - - - - - - 90 - 16 11 - - - - - - - - - - T325 RQTTAPAT MSTAASG 1 9 - - - - - - 9 - - - - - - - - - - - - - S331 ATMSTAAS GTTMGLV 2 31 - - - - - - 26 - - - - - - - - - 3 2 - - T356 ADGVKPQT NSTKNSA 1 8 - - - - - - 8 - - - - - - - - - - - - - S358 GVKPQTNS TKNSAAA 1 91 - - - - - - 91 - - - - - - - - - - - - - S362 QTNSTKNS AAATSPK 1 9 - - - - - - 9 - - - - - - - - - - - - - T366 TKNSAAAT SPKGTLP 1 27 - - - - - - 27 - - - - - - - - - - - - - S367 KNSAAATS PKGTLPP 3 131 - - - - - - 99 - - - 4 4 - - - - - - 12 12 T381 PAALEPQT TVIHNPV 1 18 - - - - - - 18 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T287 SMMHRQET VECLKKF -5.1e-20 - -3.7e-22 - - -9.7e-6 -0.1 -1.6e-3 - -0.11 - T321 FSVGRQTT APATMST - - - - - - - - - - - T325 RQTTAPAT MSTAASG - - - - - - - - - - - S331 ATMSTAAS GTTMGLV - - - - - - - - - - - T356 ADGVKPQT NSTKNSA - - - - - - - - - - - S358 GVKPQTNS TKNSAAA - - - - - - - - - - - S362 QTNSTKNS AAATSPK - - - - - - - - - - - T366 TKNSAAAT SPKGTLP - - - - - - - - - - - S367 KNSAAATS PKGTLPP - - - - - - - - - - - T381 PAALEPQT TVIHNPV - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T287
T321
T325
S331
T356
S358
S362
T366
S367
T381
T382
S394
S395
S397
T400
T401
S418
S423
S436
S441
S456
S461
T463
S471
S479
S504
T506
S513
S522
T524
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation CCRCC T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation COAD T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation GBM T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation HNSCC T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation LSCC T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation LUAD T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation OV T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation PDAC T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation UCEC T287 T321 T325 S331 T356 S358 S362 T366 S367 T381 T382 S394 S395 S397 T400 T401 S418 S423 S436 S441 S456 S461 T463 S471 S479 S504 T506 S513 S522 T524 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T287
T321
T325
S331
T356
S358
S362
T366
S367
T381
T382
S394
S395
S397
T400
T401
S418
S423
S436
S441
S456
S461
T463
S471
S479
S504
T506
S513
S522
T524
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
T287
T321
T325
S331
T356
S358
S362
T366
S367
T381
T382
S394
S395
S397
T400
T401
S418
S423
S436
S441
S456
S461
T463
S471
S479
S504
T506
S513
S522
T524
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.