ETV6: ETS variant transcription factor 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1ji7 chain A
1ji7 chain B
1ji7 chain C
1lky chain A
1lky chain B
1lky chain C
1lky chain D
1lky chain E
1lky chain F
2dao chain A
2qar chain A
2qar chain B
2qar chain D
2qar chain E
2qb0 chain A
2qb0 chain C
2qb1 chain A
2qb1 chain B
5l0p chain A
7ju2 chain A
7ju2 chain B
7n1o chain A
7n2b chain A
7n2b chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y17 IKQERISY TPPESPV 1 9 - - - - - - - - - - 5 4 - - - - - - - - T18 KQERISYT PPESPVP 10 867 6 - 4 4 88 91 90 - 92 53 59 55 26 25 82 17 66 25 68 16 S22 ISYTPPES PVPSYAS 10 560 38 - 7 7 11 7 27 - 22 13 64 58 27 23 59 12 100 43 37 5 S26 PPESPVPS YASSTPL 6 114 48 - 8 8 - - - - 7 2 - - 9 8 - - 5 3 11 5 Y27 PESPVPSY ASSTPLH 5 71 32 - 5 4 - - - - - - - - 4 4 - - 5 3 11 3 S29 SPVPSYAS STPLHVP 3 26 - - 5 4 - - - - 6 3 - - - - - - 5 3 - - S30 PVPSYASS TPLHVPV 4 44 6 - - - 8 10 9 - - - - - - - - - 8 3 - - T31 VPSYASST PLHVPVP 4 103 6 - - - 12 15 45 - - - - - - - - - - - 11 14 S47 ALRMEEDS IRLPAHL 2 26 7 - - - - - - - - - 10 9 - - - - - - - - S131 RKPRILFS PFFHPGN 1 64 - - - - - - 64 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y17 IKQERISY TPPESPV - - - - - - - - - - - T18 KQERISYT PPESPVP -0.22 - - 0.64 - -6e-8 0.92 -0.66 0.97 0.94 0.055 S22 ISYTPPES PVPSYAS -2.6e-6 - - - - -7.7e-3 -0.18 -0.26 0.71 -8.6e-9 - S26 PPESPVPS YASSTPL - - - - - - - - - - - Y27 PESPVPSY ASSTPLH - - - - - - - - - - - S29 SPVPSYAS STPLHVP - - - - - - - - - - - S30 PVPSYASS TPLHVPV - - - - - - - - - - - T31 VPSYASST PLHVPVP - - - - - - - - - - - S47 ALRMEEDS IRLPAHL - - - - - - - - - - - S131 RKPRILFS PFFHPGN - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y17
T18
S22
S26
Y27
S29
S30
T31
S47
S131
S139
T142
T161
S165
S184
T187
T188
S193
S203
S213
S236
S238
S256
S257
S271
S284
S293
S321
S323
S439
Y447
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation CCRCC Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation COAD Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation GBM Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation HNSCC Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation LSCC Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation LUAD Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation OV Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation PDAC Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation UCEC Y17 T18 S22 S26 Y27 S29 S30 T31 S47 S131 S139 T142 T161 S165 S184 T187 T188 S193 S203 S213 S236 S238 S256 S257 S271 S284 S293 S321 S323 S439 Y447 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y17
T18
S22
S26
Y27
S29
S30
T31
S47
S131
S139
T142
T161
S165
S184
T187
T188
S193
S203
S213
S236
S238
S256
S257
S271
S284
S293
S321
S323
S439
Y447
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y17
T18
S22
S26
Y27
S29
S30
T31
S47
S131
S139
T142
T161
S165
S184
T187
T188
S193
S203
S213
S236
S238
S256
S257
S271
S284
S293
S321
S323
S439
Y447
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.