Protein: ENSP00000379670
Gene: CBX3

LinkedOmicsKB © 2022-2023 Zhang Lab

CBX3:
chromobox 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S79LIEAFLNSQKAGKEK18--44----------------
S93KDGTKRKSLSDSESD1091024-29209710072-623635323227831991389518
S95GTKRKSLSDSESDDS1099247-16159710099-694238345046831988369518
S97KRKSLSDSESDDSKS1064443-1716566045-30174846292974175524299
S99KSLSDSESDDSKSKK1069249-3223959346-18914133228761748196218
S102SDSESDDSKSKKKRD222--------------142--6-
T173AFYEERLTWHSCPED61398-1212611----393654----6-
S176EERLTWHSCPEDEAQ101536122-103809710091-1086210899106978318105449518
Showing 1 to 8 of 8 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S79LIEAFLNSQKAGKEK-----------
S93KDGTKRKSLSDSESD3.4e-4-0.322.8e-19-2.0e-50.55-0.002-0.59-0.35-0.9
S95GTKRKSLSDSESDDS6.4e-4--1.4e-12-0.340.041.8e-80.14-1.4e-9-0.034
S97KRKSLSDSESDDSKS1.1e-15--4.7e-8-1.3e-37.9e-121.5e-50.12-0.076-
S99KSLSDSESDDSKSKK8.7e-7--0.354e-12---4.1e-40.038-9.2e-41.7e-4
S102SDSESDDSKSKKKRD-----------
T173AFYEERLTWHSCPED3e-9-----3e-9----
S176EERLTWHSCPEDEAQ6.7e-87-3.5e-61.8e-21-5.1e-191.2e-303.1e-161.8e-41.4e-130.047
Showing 1 to 8 of 8 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS79S93S95S97S99S102T173S176proteinRNASCNVmethylationCCRCCS79S93S95S97S99S102T173S176proteinRNASCNVmethylationCOADS79S93S95S97S99S102T173S176proteinRNASCNVmethylationGBMS79S93S95S97S99S102T173S176proteinRNASCNVmethylationHNSCCS79S93S95S97S99S102T173S176proteinRNASCNVmethylationLSCCS79S93S95S97S99S102T173S176proteinRNASCNVmethylationLUADS79S93S95S97S99S102T173S176proteinRNASCNVmethylationOVS79S93S95S97S99S102T173S176proteinRNASCNVmethylationPDACS79S93S95S97S99S102T173S176proteinRNASCNVmethylationUCECS79S93S95S97S99S102T173S176proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.