TPI1: triosephosphate isomerase 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1hti chain A
1hti chain B
1klg chain C
1klu chain C
1wyi chain A
1wyi chain B
2iam chain P
2ian chain C
2ian chain H
2ian chain M
2ian chain R
2jk2 chain A
2jk2 chain B
2vom chain A
2vom chain B
2vom chain C
2vom chain D
4br1 chain A
4br1 chain B
4e41 chain C
4e41 chain H
4poc chain A
4poc chain B
4pod chain A
4pod chain B
4unk chain A
4unk chain B
4unl chain A
4unl chain B
4zvj chain A
4zvj chain B
6c2g chain A
6c2g chain B
6c2g chain C
6c2g chain D
6d43 chain A
6d43 chain B
6nlh chain A
6nlh chain B
6nlh chain C
6nlh chain D
6nlh chain E
6nlh chain F
6nlh chain G
6nlh chain H
6up1 chain A
6up1 chain B
6up5 chain A
6up5 chain B
6up8 chain A
6up8 chain B
6upf chain A
6upf chain B
7rde chain A
7rde chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S21 KMNGRKQS LGELIGT 10 1553 122 - 103 80 97 100 99 - 108 62 108 99 110 101 83 19 105 44 95 18 T28 SLGELIGT LNAAKVP 3 75 13 - 21 12 - - - - - - 15 14 - - - - - - - - T38 AAKVPADT EVVCAPP 1 16 16 - - - - - - - - - - - - - - - - - - - T71 AQNCYKVT NGAFTGE 10 541 38 - 42 38 12 15 81 - 67 40 69 64 4 4 7 2 20 7 28 3 T76 KVTNGAFT GEISPGM 2 23 16 - 4 3 - - - - - - - - - - - - - - - - S80 GAFTGEIS PGMIKDC 10 1446 122 - 103 80 50 40 99 - 108 62 108 99 110 101 83 19 105 44 95 18 T90 MIKDCGAT WVVLGHS 5 93 - - 8 8 - - 18 - 25 18 - - - - 7 2 - - 5 2 S97 TWVVLGHS ERRHVFG 1 46 - - 32 14 - - - - - - - - - - - - - - - - S106 RRHVFGES DELIGQK 9 654 24 - 99 76 - - 64 - 80 46 35 32 62 57 21 4 25 10 10 9 S159 ADNVKDWS KVVLAYE 2 33 24 - - - - - - - - - - - - - 7 2 - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S21 KMNGRKQS LGELIGT 1.1e-8 - -3.6e-9 -0.33 - -3.2e-3 3.9e-34 5.9e-23 0.032 9.0e-4 -0.13 T28 SLGELIGT LNAAKVP -0.57 - -0.57 - - - - - - - - T38 AAKVPADT EVVCAPP - - - - - - - - - - - T71 AQNCYKVT NGAFTGE -1.3e-3 - 1 - - -1.3e-4 -0.08 - - - - T76 KVTNGAFT GEISPGM - - - - - - - - - - - S80 GAFTGEIS PGMIKDC 8.4e-90 - 1.8e-23 6.4e-5 - 7.9e-5 1.1e-34 1.5e-32 0.012 1.3e-14 6.1e-6 T90 MIKDCGAT WVVLGHS -0.26 - - - - -0.26 - - - - - S97 TWVVLGHS ERRHVFG -0.051 - -0.051 - - - - - - - - S106 RRHVFGES DELIGQK -0.046 - 3.3e-3 - - -4.5e-5 0.23 0.97 - -5.4e-6 - S159 ADNVKDWS KVVLAYE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S21
T28
T38
T71
T76
S80
T90
S97
S106
S159
T173
T176
T178
S195
S198
S204
S212
T214
S223
S236
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation CCRCC S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation COAD S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation GBM S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation HNSCC S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation LSCC S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation LUAD S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation OV S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation PDAC S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation UCEC S21 T28 T38 T71 T76 S80 T90 S97 S106 S159 T173 T176 T178 S195 S198 S204 S212 T214 S223 S236 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S21
T28
T38
T71
T76
S80
T90
S97
S106
S159
T173
T176
T178
S195
S198
S204
S212
T214
S223
S236
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S21
T28
T38
T71
T76
S80
T90
S97
S106
S159
T173
T176
T178
S195
S198
S204
S212
T214
S223
S236
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.