Protein: ENSP00000380157
Gene: MOCS2

LinkedOmicsKB © 2022-2023 Zhang Lab

MOCS2:
molybdenum cofactor synthesis 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S20LETKLPLSPPLVEDS101411104-9876606699-1045810899105978216105447218
S188ECFWASNS_______127------------------234
Showing 1 to 2 of 2 rows

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S20LETKLPLSPPLVEDS-4.6e-28-6.1e-10-6.7e-7--2.7e-13-9.3e-18-9.8e-16-3.6e-3-2.3e-5-0.22
S188ECFWASNS_______-----------
Showing 1 to 2 of 2 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
PERT-PSP_PHORBOL_ESTERS201.9e-18--0.0420.0888.6e-42.2e-47.3e-90.384.1e-51.1e-3
PERT-PSP_ANTI_CD3S201.2e-15--0.0530.0113.5e-31.1e-5-0.0568.1e-31.4e-6
KINASE-PSP_ERK1/MAPK3S205e-15-0.681.1e-50.0120.0146.6e-53.2e-30.0170.342.2e-40.066
PERT-PSP_EGFS201.9e-13-0.151.1e-59.2e-30.0349.4e-31.2e-51.6e-3-0.184.6e-40.001
PATH-NP_TSLP_PATHWAYS203.9e-13-0.95.1e-80.120.340.0453.8e-69.0e-4-0.762.3e-30.015
PATH-NP_EGFR1_PATHWAYS201.5e-11-0.620.0170.034-0.481.8e-41.6e-52.1e-3-0.161.2e-5
KINASE-PSP_PAK1S203.4e-7---6.7e-40.50.011-0.190.0920.004
KINASE-PSP_ERK2/MAPK1S203.9e-7-0.964.8e-40.0850.20.0170.0820.530.524.1e-30.18
PERT-PSP_NOCODAZOLES206.5e-6-0.128.7e-40.220.241.4e-40.370.074-0.74.4e-40.65
KINASE-PSP_CDK1S201.4e-5-0.211.1e-50.760.222.1e-40.530.220.992.6e-4-0.87
Showing 1 to 10 of 516 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS20S188proteinRNASCNVmethylationCCRCCS20S188proteinRNASCNVmethylationCOADS20S188proteinRNASCNVmethylationGBMS20S188proteinRNASCNVmethylationHNSCCS20S188proteinRNASCNVmethylationLSCCS20S188proteinRNASCNVmethylationLUADS20S188proteinRNASCNVmethylationOVS20S188proteinRNASCNVmethylationPDACS20S188proteinRNASCNVmethylationUCECS20S188proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.