Protein: ENSP00000380247
Gene: HRH1

LinkedOmicsKB © 2022-2023 Zhang Lab

HRH1:
histamine receptor H1

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S230HRELINRSLPSFSEI1091943-3224605699-573465608276761820108918
S233LINRSLPSFSEIKLR1097447-3725383499-784778719890751826118418
S235NRSLPSFSEIKLRPE118----108--------------
S271PKDAGGGSVLKSPSQ1047545-2012616554-361825235443851419
S275GGGSVLKSPSQTPKE6336----342999---353354224--5318
S277GSVLKSPSQTPKEMK2107------90-----------611
S285QTPKEMKSPVVFSQE486------27-52------42433
Y321AEGSSRDYVAVNRSH19--------------72----
S327DYVAVNRSHGQLKTD19------9-------------
S355EDQMLGDSQSFSRTD153------53-------------
Showing 1 to 10 of 15 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S230HRELINRSLPSFSEI2.6e-5-2.1e-80.41-0.0950.0151.1e-4-0.528.3e-3-7.3e-6
S233LINRSLPSFSEIKLR-7.1e-4-4.8e-13-0.07--9.1e-4-8.5e-7-2.4e-5-0.0226.8e-3-3.1e-3
S235NRSLPSFSEIKLRPE-----------
S271PKDAGGGSVLKSPSQ2.3e-9-3.3e-6-0.61-6.1e-60.001----
S275GGGSVLKSPSQTPKE-3.3e-16---1.9e-5---8.3e-6----6.7e-8
S277GSVLKSPSQTPKEMK-----------
S285QTPKEMKSPVVFSQE-----------
Y321AEGSSRDYVAVNRSH-----------
S327DYVAVNRSHGQLKTD-----------
S355EDQMLGDSQSFSRTD-----------
Showing 1 to 10 of 15 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationCCRCCS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationCOADS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationGBMS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationHNSCCS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationLSCCS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationLUADS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationOVS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationPDACS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylationUCECS230S233S235S271S275S277S285Y321S327S355S357S363S378S380T382proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.