NFE2L2: nuclear factor, erythroid 2 like 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2flu chain P
2lz1 chain A
3zgc chain C
4ifl chain P
5wfv chain P
6t7v chain I
7k28 chain P
7k29 chain P
7k2a chain P
7k2b chain P
7k2c chain P
7k2d chain P
7k2e chain P
7k2k chain P
7o7b chain A
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S215 VETTMVPS PEAKLTE 8 659 33 - 49 30 - - 9 - 78 46 94 86 88 80 - - 9 5 38 14 S433 PEKELPVS PGHRKTP 7 590 17 - 47 36 - - - - 98 56 65 58 86 77 - - 22 8 16 4
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S215 VETTMVPS PEAKLTE 0.005 - 0.014 - - -0.01 1.8e-6 0.58 - - 0.29 S433 PEKELPVS PGHRKTP 7.8e-9 - 0.18 - - -0.53 1.9e-10 7.7e-6 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S215
S433
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S215 S433 protein RNA SCNV methylation CCRCC S215 S433 protein RNA SCNV methylation COAD S215 S433 protein RNA SCNV methylation GBM S215 S433 protein RNA SCNV methylation HNSCC S215 S433 protein RNA SCNV methylation LSCC S215 S433 protein RNA SCNV methylation LUAD S215 S433 protein RNA SCNV methylation OV S215 S433 protein RNA SCNV methylation PDAC S215 S433 protein RNA SCNV methylation UCEC S215 S433 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S215
S433
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S215
S433
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.