CEP250: centrosomal protein 250
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
6oqa chain C
6oqa chain D
6oqa chain G
6oqa chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S5 ___METRS PGLNNMK 6 184 - - 16 15 - - 9 - - - 10 8 22 21 - - 4 1 65 13 S264 EKEAHERS QELIQLK 3 41 - - 4 4 - - - - - - 5 5 - - - - - - 23 - S1295 QDLQRQLS QNQEEKS 9 849 55 - 66 45 12 6 63 - 40 24 90 83 70 65 - - 81 36 95 18 T1439 EREEEVET LRGQIQE 1 9 - - - - - - 9 - - - - - - - - - - - - - S1723 PSKAQRGS LEHMKLI 3 69 9 - - - - - - - - - 14 12 17 17 - - - - - - S1927 ETRALQDS WLQAQAV 1 15 - - - - - - - - - - - - - - - - - - 13 2 S1951 ALRAESQS SRHQEEA 1 5 - - - - - - - - - - - - - - - - - - 5 - S1952 LRAESQSS RHQEEAA 1 5 - - - - - - - - - - - - - - - - - - 5 - S2132 LPHSHKTS PMEEQSL 5 178 - - 9 6 - - 72 - 10 8 - - - - - - 5 2 59 7 S2138 TSPMEEQS LKLDSLE 5 199 - - 20 17 - - - - - - 15 15 49 44 - - 8 3 23 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S5 ___METRS PGLNNMK 0.44 - - - - - - 0.29 - - 0.96 S264 EKEAHERS QELIQLK - - - - - - - - - - - S1295 QDLQRQLS QNQEEKS 6.7e-7 - 0.51 - - 1.9e-3 1.7e-7 1.6e-10 - -0.67 -0.005 T1439 EREEEVET LRGQIQE - - - - - - - - - - - S1723 PSKAQRGS LEHMKLI - - - - - - - - - - - S1927 ETRALQDS WLQAQAV - - - - - - - - - - - S1951 ALRAESQS SRHQEEA - - - - - - - - - - - S1952 LRAESQSS RHQEEAA - - - - - - - - - - - S2132 LPHSHKTS PMEEQSL - - - - - - - - - - - S2138 TSPMEEQS LKLDSLE 0.17 - -0.8 - - - - 0.026 - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S5
S264
S1295
T1439
S1723
S1927
S1951
S1952
S2132
S2138
S2143
S2189
S2229
T2233
S2234
S2322
S2332
S2390
S2392
S2394
S2433
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation CCRCC S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation COAD S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation GBM S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation HNSCC S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation LSCC S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation LUAD S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation OV S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation PDAC S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation UCEC S5 S264 S1295 T1439 S1723 S1927 S1951 S1952 S2132 S2138 S2143 S2189 S2229 T2233 S2234 S2322 S2332 S2390 S2392 S2394 S2433 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S5
S264
S1295
T1439
S1723
S1927
S1951
S1952
S2132
S2138
S2143
S2189
S2229
T2233
S2234
S2322
S2332
S2390
S2392
S2394
S2433
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S5
S264
S1295
T1439
S1723
S1927
S1951
S1952
S2132
S2138
S2143
S2189
S2229
T2233
S2234
S2322
S2332
S2390
S2392
S2394
S2433
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.