DPYSL3: dihydropyrimidinase like 3
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4bkn chain A
4bkn chain B
4cns chain A
4cns chain B
4cns chain C
4cns chain D
4cnt chain A
4cnt chain B
4cnt chain C
4cnt chain D
4cnu chain A
4cnu chain B
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S115 VVPEPESS LTEAYEK 2 36 - - 5 4 - - 27 - - - - - - - - - - - - - S259 VTKVMSKS AADLISQ 7 546 37 - - - - - 99 - - - 83 76 62 56 7 2 31 14 65 14 S265 KSAADLIS QARKKGN 1 8 - - - - - - - - - - - - - - - - - - 6 2 T288 ASLGIDGT HYWSKNW 2 18 - - - - - - - - 5 3 5 5 - - - - - - - - Y290 LGIDGTHY WSKNWAK 1 25 - - - - - - - - - - - - 13 12 - - - - - - S292 IDGTHYWS KNWAKAA 1 63 - - - - - - 63 - - - - - - - - - - - - - S402 YPRKGRIS VGSDSDL 9 542 24 - 9 8 62 64 81 - 47 25 30 27 45 41 43 7 20 9 - - S405 KGRISVGS DSDLVIW 3 30 9 - 8 - - - - - - - - - - - - - 8 5 - - S407 RISVGSDS DLVIWDP 1 17 - - - - - - - - - - - - 9 8 - - - - - - T462 EDGNLHVT QGAGRFI 1 9 - - - - - - 9 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S115 VVPEPESS LTEAYEK - - - - - - - - - - - S259 VTKVMSKS AADLISQ -5.8e-3 - - - - - -2.3e-10 -1.3e-7 - 0.001 4.8e-3 S265 KSAADLIS QARKKGN - - - - - - - - - - - T288 ASLGIDGT HYWSKNW - - - - - - - - - - - Y290 LGIDGTHY WSKNWAK - - - - - - - - - - - S292 IDGTHYWS KNWAKAA - - - - - - - - - - - S402 YPRKGRIS VGSDSDL -2.6e-16 - - -1.3e-5 - -2.4e-8 -6.7e-5 -0.014 - - - S405 KGRISVGS DSDLVIW - - - - - - - - - - - S407 RISVGSDS DLVIWDP - - - - - - - - - - - T462 EDGNLHVT QGAGRFI - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S115
S259
S265
T288
Y290
S292
S402
S405
S407
T462
S472
Y499
T507
T508
T509
T514
S518
S522
T524
S536
S539
S541
T543
S551
S564
S568
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation CCRCC S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation COAD S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation GBM S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation HNSCC S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation LSCC S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation LUAD S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation OV S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation PDAC S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation UCEC S115 S259 S265 T288 Y290 S292 S402 S405 S407 T462 S472 Y499 T507 T508 T509 T514 S518 S522 T524 S536 S539 S541 T543 S551 S564 S568 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S115
S259
S265
T288
Y290
S292
S402
S405
S407
T462
S472
Y499
T507
T508
T509
T514
S518
S522
T524
S536
S539
S541
T543
S551
S564
S568
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S115
S259
S265
T288
Y290
S292
S402
S405
S407
T462
S472
Y499
T507
T508
T509
T514
S518
S522
T524
S536
S539
S541
T543
S551
S564
S568
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.