USP47: ubiquitin specific peptidase 47
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T68 TLNLPAST PVRKLFE 1 18 - - - - - - 18 - - - - - - - - - - - - - S142 PQILLEDS SAGEDSV 3 89 - - - - - - 27 - 34 19 - - 5 4 - - - - - - S143 QILLEDSS AGEDSVH 2 50 - - - - - - 17 - 21 12 - - - - - - - - - - S162 GPLPREGS GGSTSDY 4 100 - - - - - - 9 - - - 23 21 4 5 - - - - 24 14 S165 PREGSGGS TSDYVSQ 1 8 - - - - - - - - - - - - - - - - - - 6 2 Y169 SGGSTSDY VSQSYSY 1 9 - - - - - - - - - - - - - - - - - - 7 2 S437 QTESCTDS GAENEGS 4 85 - - - - - - 43 - 16 9 5 4 4 4 - - - - - - S832 FVLLPEQS PVSYSKR 9 1428 122 - 99 76 94 94 99 - 108 62 108 99 110 101 - - 105 44 89 18 S849 YQKAGGDS GNVDDDC 4 196 - - 17 6 - - 26 - - - 73 67 4 3 - - - - - - S865 RVKGPVGS LKSVEAI 8 361 35 - - - 24 21 44 - 24 12 25 22 9 8 - - 82 34 19 2
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T68 TLNLPAST PVRKLFE - - - - - - - - - - - S142 PQILLEDS SAGEDSV 0.48 - - - - 0.48 - - - - - S143 QILLEDSS AGEDSVH 3.1e-3 - - - - 3.1e-3 - - - - - S162 GPLPREGS GGSTSDY 0.41 - - - - - 0.61 - - - 0.52 S165 PREGSGGS TSDYVSQ - - - - - - - - - - - Y169 SGGSTSDY VSQSYSY - - - - - - - - - - - S437 QTESCTDS GAENEGS - - - - - - - - - - - S832 FVLLPEQS PVSYSKR -2.4e-5 - -5.6e-15 0.18 - -5.4e-6 0.66 -2.1e-4 - 2.1e-4 -0.56 S849 YQKAGGDS GNVDDDC -1.3e-14 - - - - - -1.4e-14 - - - - S865 RVKGPVGS LKSVEAI 1.6e-4 - - 1.0e-5 - 3.1e-5 5.6e-5 - - -4.3e-7 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
T68
S142
S143
S162
S165
Y169
S437
S832
S849
S865
S868
S876
S896
S897
S899
T902
S903
S910
S917
S918
S920
T932
S933
S940
S944
S946
S964
S965
S967
S968
T970
T1008
S1013
T1015
S1017
S1025
S1088
S1353
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation CCRCC T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation COAD T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation GBM T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation HNSCC T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation LSCC T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation LUAD T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation OV T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation PDAC T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation UCEC T68 S142 S143 S162 S165 Y169 S437 S832 S849 S865 S868 S876 S896 S897 S899 T902 S903 S910 S917 S918 S920 T932 S933 S940 S944 S946 S964 S965 S967 S968 T970 T1008 S1013 T1015 S1017 S1025 S1088 S1353 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
T68
S142
S143
S162
S165
Y169
S437
S832
S849
S865
S868
S876
S896
S897
S899
T902
S903
S910
S917
S918
S920
T932
S933
S940
S944
S946
S964
S965
S967
S968
T970
T1008
S1013
T1015
S1017
S1025
S1088
S1353
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
T68
S142
S143
S162
S165
Y169
S437
S832
S849
S865
S868
S876
S896
S897
S899
T902
S903
S910
S917
S918
S920
T932
S933
S940
S944
S946
S964
S965
S967
S968
T970
T1008
S1013
T1015
S1017
S1025
S1088
S1353
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.