RELA: RELA proto-oncogene, NF-kB subunit
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1nfi chain A
1nfi chain C
2lsp chain A
2o61 chain A
3gut chain A
3gut chain C
3gut chain E
3gut chain G
3qxy chain P
3qxy chain Q
3rc0 chain P
3rc0 chain Q
4kv1 chain C
4kv1 chain D
4kv4 chain B
5u4k chain B
5urn chain B
6nv2 chain P
6qhl chain P
6qhm chain P
6yow chain P
6yox chain P
6yoy chain P
6yp2 chain P
6yp3 chain P
6yp8 chain P
6ypl chain P
6ypy chain P
6yq2 chain P
7bi3 chain P
7biq chain P
7biw chain P
7biy chain P
7bjb chain P
7bjf chain P
7bjl chain P
7bjw chain P
7bkh chain P
7let chain C
7leu chain B
7leu chain C
7lf4 chain D
7lf4 chain E
7nj9 chain P
7njb chain P
7nk3 chain P
7nk5 chain P
7nla chain P
7nle chain P
7nm1 chain P
7nm3 chain P
7nm9 chain P
7nmh chain P
7nqp chain P
7nr7 chain P
7nsv chain P
7nv4 chain P
7nvi chain P
7nws chain P
7nxs chain P
7nxt chain P
7nxw chain P
7nxy chain P
7ny4 chain P
7nye chain P
7nyf chain P
7nyg chain P
7nz6 chain P
7nzg chain P
7nzk chain P
7nzv chain P
7o34 chain P
7o3a chain P
7o3f chain P
7o3p chain P
7o3q chain P
7o3r chain P
7o3s chain P
7o57 chain P
7o59 chain P
7o5a chain P
7o5c chain P
7o5d chain P
7o5f chain P
7o5g chain P
7o5o chain P
7o5p chain P
7o5s chain P
7o5u chain P
7o5x chain P
7o6f chain P
7o6g chain P
7o6i chain P
7o6j chain P
7o6k chain P
7o6m chain P
7o6o chain P
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S42 RYKCEGRS AGSIPGE 1 14 - - - - - - - - - - - - - - - - - - 14 - S45 CEGRSAGS IPGERST 6 270 - - 12 10 - - 17 - 50 29 40 35 - - - - 40 16 21 - S51 GSIPGERS TDTTKTH 1 19 - - - - - - - - - - - - - - - - - - 16 3 S112 CPDRCIHS FQNLGIQ 3 55 - - 11 11 - - - - - - 5 5 - - - - - - 19 4 S131 RDLEQAIS QRIQTNN 1 10 - - - - - - - - - - 5 5 - - - - - - - - S180 LRLPPVLS HPIFDNR 4 103 - - - - - - 27 - - - 10 9 21 21 - - - - 13 2 S203 ICRVNRNS GSCLGGD 6 307 - - - - - - 45 - 17 11 44 39 38 32 - - 25 10 41 5 S205 RVNRNSGS CLGGDEI 5 178 - - 42 32 - - - - 15 12 15 15 22 19 - - 4 2 - - S238 PGWEARGS FSQADVH 6 210 - - 5 4 - - 71 - 6 3 14 13 - - - - 9 3 64 18 S316 FKSIMKKS PFSGPTD 1 6 - - - - - - - - - - - - - - - - - - 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S42 RYKCEGRS AGSIPGE - - - - - - - - - - - S45 CEGRSAGS IPGERST 1.4e-21 - - - - 5.4e-8 1.7e-14 - - 6.3e-4 - S51 GSIPGERS TDTTKTH - - - - - - - - - - - S112 CPDRCIHS FQNLGIQ - - - - - - - - - - - S131 RDLEQAIS QRIQTNN - - - - - - - - - - - S180 LRLPPVLS HPIFDNR -0.11 - - - - - - -0.11 - - - S203 ICRVNRNS GSCLGGD -6e-7 - - - - - -2e-10 -5.0e-5 - 0.076 - S205 RVNRNSGS CLGGDEI -0.16 - 0.31 - - - - -2.6e-3 - - - S238 PGWEARGS FSQADVH -0.096 - - - - - - - - - -0.096 S316 FKSIMKKS PFSGPTD - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S42
S45
S51
S112
S131
S180
S203
S205
S238
S316
S337
S338
S340
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation CCRCC S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation COAD S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation GBM S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation HNSCC S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation LSCC S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation LUAD S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation OV S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation PDAC S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation UCEC S42 S45 S51 S112 S131 S180 S203 S205 S238 S316 S337 S338 S340 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S42
S45
S51
S112
S131
S180
S203
S205
S238
S316
S337
S338
S340
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S42
S45
S51
S112
S131
S180
S203
S205
S238
S316
S337
S338
S340
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.