BCL6:
BCL6 transcription repressor

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S250SRPTLEVSPNVCHSN324------9---54------6-
S256VSPNVCHSNIYSPKE45523-113----54--45------
Y259NVCHSNIYSPKETIP61477-124--18---34301312134----
S260VCHSNIYSPKETIPE488------26-------3391046-
S307SKEEERPSSEDEIAL542241-88----633759547973------
S308KEEERPSSEDEIALH836326-2421--18-97551513363362--152
S330LNRKGLVSPQSPQKS858475-7148--18-6493856256--3516114
S333KGLVSPQSPQKSDCQ101271116-99767299-10862108999888491096419518
S337SPQSPQKSDCQPNSP199-------------------
S343KSDCQPNSPTESCSS101354105-9068585890-905210899110101751892388418
Showing 1 to 10 of 17 rows
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S250SRPTLEVSPNVCHSN-----------
S256VSPNVCHSNIYSPKE-----------
Y259NVCHSNIYSPKETIP-0.53------0.53----
S260VCHSNIYSPKETIPE-----------
S307SKEEERPSSEDEIAL-0.063-----0.016-0.87-0.51---
S308KEEERPSSEDEIALH-0.29-0.97---0.045-0.88---
S330LNRKGLVSPQSPQKS-4.1e-6-8.3e-5----1.4e-6-7.9e-11--0.069-
S333KGLVSPQSPQKSDCQ3.2e-14-5.8e-14--0.155.4e-170.2-0.270.650.031
S337SPQSPQKSDCQPNSP-----------
S343KSDCQPNSPTESCSS1.9e-13-0.360.52-1.4e-52.1e-136.4e-14-0.030.990.026
Showing 1 to 10 of 17 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationCCRCCS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationCOADS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationGBMS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationHNSCCS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationLSCCS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationLUADS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationOVS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationPDACS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylationUCECS250S256Y259S260S307S308S330S333S337S343S361S366S404S427S457S466S532proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.