Protein: ENSP00000384588

CYP4F11:: cytochrome P450 family 4 subfamily F member 11

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S523	VEPLGANSQ______	2	113	-	-	-	-	-	-	-	-	-	-	54	50	5	4	-	-	-	-	-	-

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Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S523	VEPLGANSQ______	7e-7	-	-	-	-	-	7e-7	-	-	-	-

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* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
chromosomal instability	S523	2.7e-6	-	-	-	-	-	2.7e-6	-	-	-	-
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	S523	1.3e-5	-	-	-	-	-	1.3e-5	-	-	-	-
Tumor Purity (WGS)	S523	3.4e-4	-	-	-	-	-	3.4e-4	-	-	-	-
HALLMARK_MTORC1_SIGNALING	S523	4.1e-4	-	-	-	-	-	4.1e-4	-	-	-	-
Tumor Purity (ABSOLUTE)	S523	4.2e-4	-	-	-	-	-	4.2e-4	-	-	-	-
HALLMARK_MYC_TARGETS_V2	S523	6.2e-4	-	-	-	-	-	6.2e-4	-	-	-	-
HALLMARK_MYC_TARGETS_V1	S523	1.4e-3	-	-	-	-	-	1.4e-3	-	-	-	-
HALLMARK_SPERMATOGENESIS	S523	1.9e-3	-	-	-	-	-	1.9e-3	-	-	-	-
KINASE-PSP_CDK5	S523	2.1e-3	-	-	-	-	-	2.1e-3	-	-	-	-
HALLMARK_MITOTIC_SPINDLE	S523	2.9e-3	-	-	-	-	-	2.9e-3	-	-	-	-

Showing 1 to 10 of 258 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
TLK1	S523	5.6e-7	-	-	-	-	-	5.6e-7	-	-	-	-
NTRK2	S523	1.5e-5	-	-	-	-	-	1.5e-5	-	-	-	-
CDK9	S523	4.6e-5	-	-	-	-	-	4.6e-5	-	-	-	-
FAM20B	S523	7.3e-5	-	-	-	-	-	7.3e-5	-	-	-	-
IGF1R	S523	2.4e-4	-	-	-	-	-	2.4e-4	-	-	-	-
TTK	S523	2.9e-4	-	-	-	-	-	2.9e-4	-	-	-	-
GTF2F1	S523	4.6e-4	-	-	-	-	-	4.6e-4	-	-	-	-
EPHB3	S523	4.7e-4	-	-	-	-	-	4.7e-4	-	-	-	-
WNK2	S523	6.5e-4	-	-	-	-	-	6.5e-4	-	-	-	-
ATR	S523	1.2e-3	-	-	-	-	-	1.2e-3	-	-	-	-

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* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
SYNJ1	S523	-1.3e-5	-	-	-	-	-	-1.4e-5	-	-	-	-
ACP2	S523	-1.7e-5	-	-	-	-	-	-1.7e-5	-	-	-	-
LPIN2	S523	-6.7e-5	-	-	-	-	-	-6.7e-5	-	-	-	-
PPP3CB	S523	-1.2e-4	-	-	-	-	-	-1.2e-4	-	-	-	-
PHPT1	S523	-1.9e-4	-	-	-	-	-	-1.9e-4	-	-	-	-
PTPRM	S523	-3.0e-4	-	-	-	-	-	-3.0e-4	-	-	-	-
PTEN	S523	-8.0e-4	-	-	-	-	-	-8.0e-4	-	-	-	-
PPM1M	S523	-8.3e-4	-	-	-	-	-	-8.3e-4	-	-	-	-
SSH1	S523	-1.6e-3	-	-	-	-	-	-1.6e-3	-	-	-	-
INPP5B	S523	-0.002	-	-	-	-	-	-0.002	-	-	-	-

Showing 1 to 10 of 240 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000384588Gene: CYP4F11

Lollipop plot

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000384588
Gene: CYP4F11