SETD5: SET domain containing 5
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S72 SDLNGLPS PVEERCG 7 884 - - 41 31 - - 45 - 97 55 98 91 100 93 - - 90 36 89 18 S81 VEERCGDS PNSEGET 3 36 - - - - - - - - - - 5 5 4 5 - - - - 12 5 S84 RCGDSPNS EGETVPT 2 26 - - - - - - - - - - - - 4 5 - - - - 12 5 S193 KKIKNSPS EAQNLDE 3 73 - - - - - - 18 - - - - - - - - - 13 5 23 14 S477 PEKVTVSS DHEEVDN 7 558 - - 4 4 - - 55 - 84 51 93 86 31 28 - - 29 11 64 18 S541 QPLEQSNS DVEITTT 7 537 - - 39 28 - - 35 - 50 31 59 54 67 61 - - 13 5 77 18 S578 VSNVTIPS TPQSVGV 1 13 - - - - - - - - - - - - - - - - - - 13 - S591 GVNTRRSS QAGDIAA 7 839 - - 47 39 - - 53 - 80 45 93 84 74 68 - - 100 43 95 18 S852 TKLLRPLS PVTPPPP 7 595 - - 4 4 - - 18 - 108 62 89 82 88 80 - - 3 2 46 9 T855 LRPLSPVT PPPPNSG 7 471 - - 8 8 - - 90 - 5 4 89 82 12 12 - - 105 44 12 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S72 SDLNGLPS PVEERCG 1.5e-4 - -0.013 - - 2.4e-4 1.3e-17 1.3e-11 - -8.1e-11 -0.49 S81 VEERCGDS PNSEGET - - - - - - - - - - - S84 RCGDSPNS EGETVPT - - - - - - - - - - - S193 KKIKNSPS EAQNLDE -0.65 - - - - - - - - - -0.65 S477 PEKVTVSS DHEEVDN 1.4e-3 - - - - -0.49 4.8e-19 2.3e-5 - -8.3e-5 -0.49 S541 QPLEQSNS DVEITTT 2.5e-6 - 0.011 - - -0.97 6.7e-8 4.7e-7 - - -0.016 S578 VSNVTIPS TPQSVGV - - - - - - - - - - - S591 GVNTRRSS QAGDIAA 0.037 - 0.025 - - -0.96 0.018 9.6e-13 - -7.3e-6 -0.034 S852 TKLLRPLS PVTPPPP 1.8e-11 - - - - -0.54 2.3e-11 2.5e-8 - - - T855 LRPLSPVT PPPPNSG -0.77 - - - - - 2.3e-11 - - -1.3e-12 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S72
S81
S84
S193
S477
S541
S578
S591
S852
T855
S863
S865
S890
T903
S1020
S1043
S1131
S1180
S1198
T1200
S1203
S1233
S1246
S1260
S1269
T1348
S1353
S1355
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation CCRCC S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation COAD S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation GBM S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation HNSCC S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation LSCC S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation LUAD S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation OV S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation PDAC S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation UCEC S72 S81 S84 S193 S477 S541 S578 S591 S852 T855 S863 S865 S890 T903 S1020 S1043 S1131 S1180 S1198 T1200 S1203 S1233 S1246 S1260 S1269 T1348 S1353 S1355 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S72
S81
S84
S193
S477
S541
S578
S591
S852
T855
S863
S865
S890
T903
S1020
S1043
S1131
S1180
S1198
T1200
S1203
S1233
S1246
S1260
S1269
T1348
S1353
S1355
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S72
S81
S84
S193
S477
S541
S578
S591
S852
T855
S863
S865
S890
T903
S1020
S1043
S1131
S1180
S1198
T1200
S1203
S1233
S1246
S1260
S1269
T1348
S1353
S1355
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.