PRPF40A: pre-mRNA processing factor 40 homolog A
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S10 SGSGRRRS SLSPTMR 7 83 6 - 8 - - - - - 5 4 5 4 9 8 - - 4 2 19 9 S11 GSGRRRSS LSPTMRP 7 85 14 - - - - - - - 7 3 5 5 9 8 8 1 13 3 7 2 S13 GRRRSSLS PTMRPGT 9 753 59 - 13 10 - - 18 - 91 52 98 89 43 40 58 12 56 24 72 18 S124 SMWTEHKS PDGRTYY 5 150 40 - - - 23 13 - - - - 15 14 10 8 - - 21 6 - - T149 EKPDDLKT PAEQLLS 1 10 - - - - - - - - 7 3 - - - - - - - - - - S167 WKEYKSDS GKPYYYN 1 17 17 - - - - - - - - - - - - - - - - - - - T346 QETVADFT PKKEEEE 10 1437 122 - 99 76 46 43 99 - 108 62 108 99 110 101 83 19 105 44 95 18 S354 PKKEEEES QPAKKTY 6 241 43 - - - - - 9 - - - 49 43 21 20 - - 34 14 6 2 Y401 MIINDPRY SALAKLS 1 46 - - - - - - 46 - - - - - - - - - - - - - S402 IINDPRYS ALAKLSE 1 46 - - - - - - 46 - - - - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S10 SGSGRRRS SLSPTMR - - - - - - - - - - - S11 GSGRRRSS LSPTMRP - - - - - - - - - - - S13 GRRRSSLS PTMRPGT 1.8e-42 - - - - 8.2e-10 2.6e-28 9.5e-11 2.8e-3 0.037 2.2e-6 S124 SMWTEHKS PDGRTYY 4.9e-4 - - 4.9e-4 - - - - - - - T149 EKPDDLKT PAEQLLS - - - - - - - - - - - S167 WKEYKSDS GKPYYYN - - - - - - - - - - - T346 QETVADFT PKKEEEE 2.8e-62 - 2.2e-4 1.6e-6 - 3.4e-16 1e-34 4.1e-33 7.2e-5 -0.19 4.2e-4 S354 PKKEEEES QPAKKTY 0.016 - - - - - 0.016 0.1 - 0.9 - Y401 MIINDPRY SALAKLS - - - - - - - - - - - S402 IINDPRYS ALAKLSE - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S10
S11
S13
S124
T149
S167
T346
S354
Y401
S402
S696
S721
S760
S782
S801
S803
S805
S807
S825
S827
S830
S831
S832
S835
S856
S858
S861
S876
S900
T905
S906
S908
S911
T921
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation CCRCC S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation COAD S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation GBM S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation HNSCC S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation LSCC S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation LUAD S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation OV S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation PDAC S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation UCEC S10 S11 S13 S124 T149 S167 T346 S354 Y401 S402 S696 S721 S760 S782 S801 S803 S805 S807 S825 S827 S830 S831 S832 S835 S856 S858 S861 S876 S900 T905 S906 S908 S911 T921 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S10
S11
S13
S124
T149
S167
T346
S354
Y401
S402
S696
S721
S760
S782
S801
S803
S805
S807
S825
S827
S830
S831
S832
S835
S856
S858
S861
S876
S900
T905
S906
S908
S911
T921
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S10
S11
S13
S124
T149
S167
T346
S354
Y401
S402
S696
S721
S760
S782
S801
S803
S805
S807
S825
S827
S830
S831
S832
S835
S856
S858
S861
S876
S900
T905
S906
S908
S911
T921
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.