Protein: ENSP00000387207
Gene: AFF3

LinkedOmicsKB © 2022-2023 Zhang Lab

AFF3:
AF4/FMR2 family member 3

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S248QDQAPDESPKLKSSS4796-44--9-----------4412
S373LEDDLKLSSDEEENE34024-----9-----------7-
S374EDDLKLSSDEEENEQ34024-----9-----------7-
S393RTALRALSDSAVVQQ412520---------5588----6613
S549SKGVKQKSPPAAVAV12525-------------------
S755FGRNELLSPLKDSDE514670-----18---151354----1011
S878KNEKMLRSPISPLSD36814-1212--------------246
S881KMLRSPISPLSDASK940396-258--46-241015154439721673316
S954RPQTKPWSPGSNGHR515079-88--9---201844------
S1010NYAEAALSFIECGNA358--44------8101814------
Showing 1 to 10 of 11 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S248QDQAPDESPKLKSSS-0.042----------0.042
S373LEDDLKLSSDEEENE-----------
S374EDDLKLSSDEEENEQ-----------
S393RTALRALSDSAVVQQ-1.8e-5----------1.8e-5
S549SKGVKQKSPPAAVAV-----------
S755FGRNELLSPLKDSDE-----------
S878KNEKMLRSPISPLSD-----------
S881KMLRSPISPLSDASK-5.2e-12-----0.21--1.8e-15---6.1e-3
S954RPQTKPWSPGSNGHR-1.7e-4------1.7e-4----
S1010NYAEAALSFIECGNA-----------
Showing 1 to 10 of 11 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationCCRCCS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationCOADS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationGBMS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationHNSCCS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationLSCCS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationLUADS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationOVS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationPDACS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylationUCECS248S373S374S393S549S755S878S881S954S1010S1105proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.