IMMT: inner membrane mitochondrial protein
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
Y33 PLRPCRRY STSGSSG 2 15 - - - - - - 9 - - - - - - - - - 4 2 - - S34 LRPCRRYS TSGSSGL 6 260 - - - - - - 54 - 52 31 5 4 4 4 - - 35 14 43 14 T35 RPCRRYST SGSSGLT 1 9 - - - - - - - - - - - - 5 4 - - - - - - S103 NVPLPKKS IQSGPLK 8 550 - - 46 35 - - 80 - 57 33 54 50 55 47 28 6 8 4 43 4 S106 LPKKSIQS GPLKISS 7 223 - - 40 31 - - 26 - - - 25 24 4 4 29 6 12 6 7 9 S112 QSGPLKIS SVSEVMK 3 31 - - 4 4 - - - - - - - - - - 7 1 - - 13 2 S113 SGPLKISS VSEVMKE 8 580 - - 61 48 - - 37 - 36 19 55 48 75 68 20 4 24 11 56 18 S115 PLKISSVS EVMKESK 8 243 - - 17 15 - - 35 - 6 3 25 24 8 8 32 9 3 2 49 7 S121 VSEVMKES KQPASQL 4 47 - - 13 10 - - 9 - - - 5 4 - - - - - - 6 - S126 KESKQPAS QLQKQKG 2 17 - - 4 4 - - - - 5 4 - - - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Y33 PLRPCRRY STSGSSG - - - - - - - - - - - S34 LRPCRRYS TSGSSGL -0.38 - - - - 3.3e-4 - - - -5.3e-3 -0.02 T35 RPCRRYST SGSSGLT - - - - - - - - - - - S103 NVPLPKKS IQSGPLK 1.8e-3 - -0.01 - - 1 6.2e-5 7.3e-5 - - - S106 LPKKSIQS GPLKISS -2.0e-4 - -1.3e-11 - - - 0.13 - - - - S112 QSGPLKIS SVSEVMK - - - - - - - - - - - S113 SGPLKISS VSEVMKE -1.7e-7 - -3.3e-11 - - -0.11 0.87 -3.6e-4 - -0.66 -0.45 S115 PLKISSVS EVMKESK -0.048 - - - - - -0.048 - - - - S121 VSEVMKES KQPASQL - - - - - - - - - - - S126 KESKQPAS QLQKQKG - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
Y33
S34
T35
S103
S106
S112
S113
S115
S121
S126
S138
S186
S190
S191
S192
S193
S233
S263
T276
S350
S356
S388
S390
T398
S447
S458
S507
S514
S528
S583
S584
T587
T589
S594
S604
Y696
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation CCRCC Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation COAD Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation GBM Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation HNSCC Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation LSCC Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation LUAD Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation OV Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation PDAC Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation UCEC Y33 S34 T35 S103 S106 S112 S113 S115 S121 S126 S138 S186 S190 S191 S192 S193 S233 S263 T276 S350 S356 S388 S390 T398 S447 S458 S507 S514 S528 S583 S584 T587 T589 S594 S604 Y696 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
Y33
S34
T35
S103
S106
S112
S113
S115
S121
S126
S138
S186
S190
S191
S192
S193
S233
S263
T276
S350
S356
S388
S390
T398
S447
S458
S507
S514
S528
S583
S584
T587
T589
S594
S604
Y696
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
Y33
S34
T35
S103
S106
S112
S113
S115
S121
S126
S138
S186
S190
S191
S192
S193
S233
S263
T276
S350
S356
S388
S390
T398
S447
S458
S507
S514
S528
S583
S584
T587
T589
S594
S604
Y696
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.