CLINT1: clathrin interactor 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1xgw chain A
2qy7 chain A
2qy7 chain B
2qy7 chain C
2v8s chain E
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S110 EHIYDLRS LENYHFV 2 13 - - 8 - - - - - - - - - - - - - 3 2 - - S163 KDKYVGVS SDSVGGF 4 121 23 - - - - - - - 12 7 14 14 27 24 - - - - - - S164 DKYVGVSS DSVGGFR 2 23 9 - 7 7 - - - - - - - - - - - - - - - - S166 YVGVSSDS VGGFRYS 9 565 25 - - - 52 55 55 - 41 23 25 23 17 16 26 7 60 27 95 18 Y172 DSVGGFRY SERYDPE 1 10 - - - - - - - - - - 5 5 - - - - - - - - S173 SVGGFRYS ERYDPEP 8 478 - - 18 16 - - 9 - 51 28 39 37 90 80 35 7 5 1 56 6 Y176 GFRYSERY DPEPKSK 2 20 6 - 7 7 - - - - - - - - - - - - - - - - S182 RYDPEPKS KWDEEWD 3 76 6 - - - - - - - - - 20 19 16 15 - - - - - - S205 SDKLGELS DKIGSTI 10 877 96 - 91 68 39 42 26 - 28 18 73 67 67 59 7 1 99 41 53 2 S210 ELSDKIGS TIDDTIS 8 275 16 - - - 11 16 27 - 6 4 20 18 8 9 - - 43 16 74 7
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S110 EHIYDLRS LENYHFV - - - - - - - - - - - S163 KDKYVGVS SDSVGGF 0.58 - - - - - - 0.58 - - - S164 DKYVGVSS DSVGGFR - - - - - - - - - - - S166 YVGVSSDS VGGFRYS 7e-9 - - -0.29 - 0.062 3.7e-4 - - 7.4e-7 2.7e-4 Y172 DSVGGFRY SERYDPE - - - - - - - - - - - S173 SVGGFRYS ERYDPEP 6.4e-5 - - - - 0.19 -0.025 3.5e-15 - - - Y176 GFRYSERY DPEPKSK - - - - - - - - - - - S182 RYDPEPKS KWDEEWD -1.9e-5 - - - - - -1.9e-5 - - - - S205 SDKLGELS DKIGSTI 0.39 - -2.1e-5 0.008 - 3.7e-3 -0.87 2.6e-6 - -1.8e-4 - S210 ELSDKIGS TIDDTIS 0.1 - - - - - 0.22 - - 0.27 -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S110
S163
S164
S166
Y172
S173
Y176
S182
S205
S210
T211
S227
S232
S234
S245
T284
Y293
T294
S299
S305
T306
T308
S311
S312
S459
S478
S481
S485
S624
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation CCRCC S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation COAD S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation GBM S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation HNSCC S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation LSCC S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation LUAD S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation OV S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation PDAC S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation UCEC S110 S163 S164 S166 Y172 S173 Y176 S182 S205 S210 T211 S227 S232 S234 S245 T284 Y293 T294 S299 S305 T306 T308 S311 S312 S459 S478 S481 S485 S624 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S110
S163
S164
S166
Y172
S173
Y176
S182
S205
S210
T211
S227
S232
S234
S245
T284
Y293
T294
S299
S305
T306
T308
S311
S312
S459
S478
S481
S485
S624
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S110
S163
S164
S166
Y172
S173
Y176
S182
S205
S210
T211
S227
S232
S234
S245
T284
Y293
T294
S299
S305
T306
T308
S311
S312
S459
S478
S481
S485
S624
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.