NFATC1: nuclear factor of activated T cells 1
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
1a66 chain A
1nfa chain A
5sve chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S151 VLPSSKRS PSTATLS 4 69 - - 4 4 - - 9 - 5 4 - - 24 19 - - - - - - S153 PSSKRSPS TATLSLP 3 49 - - - - - - 9 - 6 4 15 15 - - - - - - - - S158 SPSTATLS LPSLEAY 1 8 - - - - - - - - - - 4 4 - - - - - - - - Y165 SLPSLEAY RDPSCLS 1 9 - - - - - - - - - - 5 4 - - - - - - - - S172 YRDPSCLS PASSLSS 1 6 - - 3 3 - - - - - - - - - - - - - - - - S211 PWQSPCVS PKTTDPE 3 62 - - - - - - - - 12 4 10 9 - - - - - - 23 4 S233 GACTLLGS PRHSPST 7 1068 - - 98 76 - - 90 - 92 52 108 99 110 101 - - 96 42 95 9 S237 LLGSPRHS PSTSPRA 7 135 - - 4 4 - - 37 - 5 4 20 18 18 14 - - 4 2 5 - S239 GSPRHSPS TSPRASV 4 45 - - 9 8 - - - - 6 3 5 5 5 4 - - - - - - T240 SPRHSPST SPRASVT 6 123 - - 9 8 - - - - 10 6 20 20 17 16 - - 8 3 6 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S151 VLPSSKRS PSTATLS 0.8 - - - - - - 0.8 - - - S153 PSSKRSPS TATLSLP - - - - - - - - - - - S158 SPSTATLS LPSLEAY - - - - - - - - - - - Y165 SLPSLEAY RDPSCLS - - - - - - - - - - - S172 YRDPSCLS PASSLSS - - - - - - - - - - - S211 PWQSPCVS PKTTDPE - - - - - - - - - - - S233 GACTLLGS PRHSPST -5.9e-7 - 0.49 - - -7.1e-8 -0.35 -0.36 - -3.5e-6 - S237 LLGSPRHS PSTSPRA -0.87 - - - - - -0.87 - - - - S239 GSPRHSPS TSPRASV - - - - - - - - - - - T240 SPRHSPST SPRASVT -2.9e-4 - - - - - -2.9e-4 - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S151
S153
S158
Y165
S172
S211
S233
S237
S239
T240
S241
S245
S256
S257
S261
S269
S278
S282
T284
S286
S290
T339
S359
S403
T405
Y407
S670
S765
S772
S813
S887
S903
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation CCRCC S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation COAD S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation GBM S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation HNSCC S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation LSCC S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation LUAD S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation OV S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation PDAC S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation UCEC S151 S153 S158 Y165 S172 S211 S233 S237 S239 T240 S241 S245 S256 S257 S261 S269 S278 S282 T284 S286 S290 T339 S359 S403 T405 Y407 S670 S765 S772 S813 S887 S903 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S151
S153
S158
Y165
S172
S211
S233
S237
S239
T240
S241
S245
S256
S257
S261
S269
S278
S282
T284
S286
S290
T339
S359
S403
T405
Y407
S670
S765
S772
S813
S887
S903
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S151
S153
S158
Y165
S172
S211
S233
S237
S239
T240
S241
S245
S256
S257
S261
S269
S278
S282
T284
S286
S290
T339
S359
S403
T405
Y407
S670
S765
S772
S813
S887
S903
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.