Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
4yqf chain A
4yqf chain B
5cyo chain A
5cyo chain B
5cyp chain A
5cyp chain B
5cyp chain C
5cyp chain D
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S4 ____MKKS YSGGTRT 5 108 - - - - - - - - - - 10 9 4 4 41 10 9 5 12 4 Y5 ___MKKSY SGGTRTS 1 24 - - - - - - - - - - - - - - 19 5 - - - - S6 __MKKSYS GGTRTSS 1 18 - - - - - - 18 - - - - - - - - - - - - - T11 SYSGGTRT SSGRLRR 5 136 32 - 4 4 - - - - 29 16 9 9 19 14 - - - - - - S12 YSGGTRTS SGRLRRL 7 225 59 - 33 28 - - - - 12 3 24 22 4 4 - - 5 1 28 2 S13 SGGTRTSS GRLRRLG 3 40 6 - 17 8 - - - - - - 5 4 - - - - - - - - S22 RLRRLGDS SGPALKR 10 1358 122 - 103 80 87 83 17 - 108 62 84 77 110 101 56 12 105 44 89 18 S23 LRRLGDSS GPALKRS 8 203 14 - 33 31 - - - - 7 3 15 13 9 8 7 2 3 2 50 6 S30 SGPALKRS FEVEEVE 9 1261 122 - 103 80 12 14 99 - 102 59 103 94 110 101 - - 105 44 95 18 T38 FEVEEVET PNSTPPR 6 198 18 - 42 30 - - - - 10 7 14 13 9 8 - - - - 42 5
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S4 ____MKKS YSGGTRT 1.2e-3 - - - - - - - 1.2e-3 - - Y5 ___MKKSY SGGTRTS - - - - - - - - - - - S6 __MKKSYS GGTRTSS - - - - - - - - - - - T11 SYSGGTRT SSGRLRR 8.5e-5 - - - - 8.5e-5 - - - - - S12 YSGGTRTS SGRLRRL 1.8e-5 - 0.43 - - - 1.3e-7 - - - - S13 SGGTRTSS GRLRRLG - - - - - - - - - - - S22 RLRRLGDS SGPALKR 1.3e-19 - 2.5e-27 -2.0e-6 - 2.4e-9 0.014 1.4e-14 -0.68 6.4e-13 -7.6e-4 S23 LRRLGDSS GPALKRS 6.5e-11 - 6.5e-11 - - - - - - - - S30 SGPALKRS FEVEEVE 6.3e-5 - 1.2e-24 - - 2.1e-14 -0.64 -0.081 - 0.66 -1.9e-5 T38 FEVEEVET PNSTPPR 1.2e-11 - 1.2e-11 - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S4
Y5
S6
T11
S12
S13
S22
S23
S30
T38
S41
T42
T49
S58
S59
S71
S80
S82
S85
S89
S96
S111
T142
S160
T177
S203
T207
S211
T235
S238
S247
T255
Y278
S327
S332
S421
Y473
S482
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation CCRCC S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation COAD S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation GBM S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation HNSCC S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation LSCC S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation LUAD S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation OV S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation PDAC S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation UCEC S4 Y5 S6 T11 S12 S13 S22 S23 S30 T38 S41 T42 T49 S58 S59 S71 S80 S82 S85 S89 S96 S111 T142 S160 T177 S203 T207 S211 T235 S238 S247 T255 Y278 S327 S332 S421 Y473 S482 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S4
Y5
S6
T11
S12
S13
S22
S23
S30
T38
S41
T42
T49
S58
S59
S71
S80
S82
S85
S89
S96
S111
T142
S160
T177
S203
T207
S211
T235
S238
S247
T255
Y278
S327
S332
S421
Y473
S482
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S4
Y5
S6
T11
S12
S13
S22
S23
S30
T38
S41
T42
T49
S58
S59
S71
S80
S82
S85
S89
S96
S111
T142
S160
T177
S203
T207
S211
T235
S238
S247
T255
Y278
S327
S332
S421
Y473
S482
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.