ASXL2: ASXL transcriptional regulator 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S136 SRWKRKVS SSSPQSG 5 101 - - 8 - - - - - - - - - 4 4 7 1 43 17 12 5 S137 RWKRKVSS SSPQSGC 4 37 - - 8 8 - - - - - - - - 4 4 - - 3 2 5 3 S138 WKRKVSSS SPQSGCP 3 30 - - 13 4 - - 9 - - - - - - - - - - - 4 - S139 KRKVSSSS PQSGCPS 10 571 31 - 25 14 16 11 81 - 12 7 50 47 28 23 26 7 68 28 79 18 S142 VSSSSPQS GCPSPTI 3 64 26 - - - - - - - - - 4 4 - - - - - - 23 7 S146 SPQSGCPS PTIPAGK 10 1054 99 - 75 68 6 11 26 - 108 62 93 86 98 89 26 8 79 35 70 15 S156 IPAGKVIS PSQKHSK 8 503 32 - - - - - 53 - 60 35 70 62 28 24 36 7 40 18 25 13 T222 GKQSDGQT GSPQNSN 1 7 - - - - - - - - - - - - - - - - - - 5 2 S224 QSDGQTGS PQNSNSS 10 1049 55 - 29 28 51 47 99 - 84 51 94 86 105 97 7 2 71 30 95 18 S228 QTGSPQNS NSSFSSS 2 26 17 - - - - - - - - - 5 4 - - - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S136 SRWKRKVS SSSPQSG -0.15 - - - - - - - - -0.15 - S137 RWKRKVSS SSPQSGC - - - - - - - - - - - S138 WKRKVSSS SPQSGCP - - - - - - - - - - - S139 KRKVSSSS PQSGCPS 5.9e-9 - -0.076 - - - 2.1e-16 1.4e-3 - -0.6 9.2e-5 S142 VSSSSPQS GCPSPTI - - - - - - - - - - - S146 SPQSGCPS PTIPAGK 3.4e-16 - 0.74 - - 0.016 1.8e-21 3e-15 - -1.7e-3 0.003 S156 IPAGKVIS PSQKHSK 7.3e-4 - - - - 0.14 4.7e-3 5.8e-7 - -2.5e-4 0.056 T222 GKQSDGQT GSPQNSN - - - - - - - - - - - S224 QSDGQTGS PQNSNSS 1.6e-17 - -0.26 5.1e-8 - 0.037 1e-24 1.3e-14 - -4.5e-4 1 S228 QTGSPQNS NSSFSSS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S136
S137
S138
S139
S142
S146
S156
T222
S224
S228
S395
S397
S439
S440
T523
S524
S530
S562
S570
S571
T573
S600
S634
S637
S714
S717
S794
S834
T836
S842
S845
T883
S885
T888
S1143
S1153
S1154
T1181
S1185
T1186
T1255
S1284
S1285
S1300
T1302
S1319
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation CCRCC S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation COAD S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation GBM S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation HNSCC S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation LSCC S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation LUAD S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation OV S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation PDAC S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation UCEC S136 S137 S138 S139 S142 S146 S156 T222 S224 S228 S395 S397 S439 S440 T523 S524 S530 S562 S570 S571 T573 S600 S634 S637 S714 S717 S794 S834 T836 S842 S845 T883 S885 T888 S1143 S1153 S1154 T1181 S1185 T1186 T1255 S1284 S1285 S1300 T1302 S1319 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S136
S137
S138
S139
S142
S146
S156
T222
S224
S228
S395
S397
S439
S440
T523
S524
S530
S562
S570
S571
T573
S600
S634
S637
S714
S717
S794
S834
T836
S842
S845
T883
S885
T888
S1143
S1153
S1154
T1181
S1185
T1186
T1255
S1284
S1285
S1300
T1302
S1319
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S136
S137
S138
S139
S142
S146
S156
T222
S224
S228
S395
S397
S439
S440
T523
S524
S530
S562
S570
S571
T573
S600
S634
S637
S714
S717
S794
S834
T836
S842
S845
T883
S885
T888
S1143
S1153
S1154
T1181
S1185
T1186
T1255
S1284
S1285
S1300
T1302
S1319
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.