Protein: ENSP00000391447
Gene: ASXL2

LinkedOmicsKB © 2022-2023 Zhang Lab

ASXL2:
ASXL transcriptional regulator 2

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S136SRWKRKVSSSSPQSG5101--8---------44714317125
S137RWKRKVSSSSPQSGC437--88--------44--3253
S138WKRKVSSSSPQSGCP330--134--9-----------4-
S139KRKVSSSSPQSGCPS1057131-2514161181-1275047282326768287918
S142VSSSSPQSGCPSPTI36426---------44------237
S146SPQSGCPSPTIPAGK10105499-756861126-108629386988926879357015
S156IPAGKVISPSQKHSK850332-----53-60357062282436740182513
T222GKQSDGQTGSPQNSN17------------------52
S224QSDGQTGSPQNSNSS10104955-2928514799-84519486105977271309518
S228QTGSPQNSNSSFSSS22617---------54--------
Showing 1 to 10 of 46 rows
102550
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S136SRWKRKVSSSSPQSG-0.15---------0.15-
S137RWKRKVSSSSPQSGC-----------
S138WKRKVSSSSPQSGCP-----------
S139KRKVSSSSPQSGCPS5.9e-9--0.076---2.1e-161.4e-3--0.69.2e-5
S142VSSSSPQSGCPSPTI-----------
S146SPQSGCPSPTIPAGK3.4e-16-0.74--0.0161.8e-213e-15--1.7e-30.003
S156IPAGKVISPSQKHSK7.3e-4----0.144.7e-35.8e-7--2.5e-40.056
T222GKQSDGQTGSPQNSN-----------
S224QSDGQTGSPQNSNSS1.6e-17--0.265.1e-8-0.0371e-241.3e-14--4.5e-41
S228QTGSPQNSNSSFSSS-----------
Showing 1 to 10 of 46 rows
102550
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationCCRCCS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationCOADS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationGBMS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationHNSCCS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationLSCCS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationLUADS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationOVS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationPDACS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylationUCECS136S137S138S139S142S146S156T222S224S228S395S397S439S440T523S524S530S562S570S571T573S600S634S637S714S717S794S834T836S842S845T883S885T888S1143S1153S1154T1181S1185T1186T1255S1284S1285S1300T1302S1319proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.