FAM126B:
family with sequence similarity 126 member B

Lollipop plot

Phosphosites location and occurrence

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Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T306KVLKVEVTPTVPRIS101223113-9572402382-714293849788681795418616
T319ISRTAITTASIRRHR19------9-------------
S321RTAITTASIRRHRWR101306122-79729710072-513198908781831910544687
S341GVNGGEESVNLNDAD35224-54------109--------
S398SAIKSSESPRDSVVR1098396-9976373572-372268616357681580314818
S402SSESPRDSVVRKQYV1091398-7462535426-372010394787368171262711
S416VQQPTDLSVDSVELT863239-9573--35-683934318981--146244
S419PTDLSVDSVELTPMK3236-----9-----------53
S430TPMKKHLSLPAGQVV101510122-9976939599-10862103951101017518105448718
S442QVVPKINSLSLIRTA986530-50374131--734598897972751727117713
Showing 1 to 10 of 17 rows
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
T306KVLKVEVTPTVPRIS-1--0.0390.16-0.41-0.83-0.466.8e-6-2.8e-70.16
T319ISRTAITTASIRRHR-----------
S321RTAITTASIRRHRWR-1.4e-11--0.81-1.3e-20--0.3-1.5e-4-0.130.71-0.018-
S341GVNGGEESVNLNDAD-----------
S398SAIKSSESPRDSVVR8.7e-9-0.513.9e-3-0.125.2e-62.6e-30.0670.90.1
S402SSESPRDSVVRKQYV-6.2e-8--3.3e-6-3.6e-13-0.51-2.4e-44.8e-30.074--6.6e-5
S416VQQPTDLSVDSVELT0.43-7.5e-12---4e-8-0.170.11---
S419PTDLSVDSVELTPMK-----------
S430TPMKKHLSLPAGQVV-3.7e-10-5.3e-9-5.8e-16--0.55-2.4e-13-3.7e-80.016-1.2e-70.4
S442QVVPKINSLSLIRTA9.9e-8--5.0e-5-0.16-0.131.2e-110.0033.4e-66.2e-30.057
Showing 1 to 10 of 17 rows
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationCCRCCT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationCOADT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationGBMT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationHNSCCT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationLSCCT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationLUADT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationOVT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationPDACT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylationUCECT306T319S321S341S398S402S416S419S430S442T448S450S456Y459S491S508S521proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.