Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2coa chain A
3bgm chain C
4nnx chain C
4nny chain C
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S183 YHKRCAFS IPNNCSG 1 8 - - - - - - - - - - - - - - - - - - 8 - S189 FSIPNNCS GARKRRL 6 163 26 - 4 4 - - - - - - 19 17 4 3 15 2 - - 60 9 S197 GARKRRLS STSLASG 10 1128 82 - 26 24 86 93 89 - 102 59 68 63 57 52 83 18 100 41 69 16 S198 ARKRRLSS TSLASGH 10 212 9 - 16 8 4 5 63 - 6 3 4 4 4 4 13 3 8 3 48 7 T199 RKRRLSST SLASGHS 5 61 8 - - - - - - - 10 7 10 9 4 4 - - 7 2 - - S200 KRRLSSTS LASGHSV 8 264 15 - 12 4 27 26 54 - 12 6 5 5 - - 44 9 - - 41 4 S203 LSSTSLAS GHSVRLG 3 151 - - - - - - 63 - - - - - - - 23 2 - - 47 16 S206 TSLASGHS VRLGTSE 8 268 - - - - 33 38 36 - 6 3 5 4 10 8 57 12 29 10 6 11 T211 GHSVRLGT SESLPCT 1 16 - - - - - - - - - - - - - - - - - - 12 4 S214 VRLGTSES LPCTAEE 10 1161 67 - 38 34 97 100 89 - 75 44 73 67 70 64 73 18 98 41 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S183 YHKRCAFS IPNNCSG - - - - - - - - - - - S189 FSIPNNCS GARKRRL - - - - - - - - - - - S197 GARKRRLS STSLASG 0.98 - -0.77 0.24 - 0.83 -0.093 -9.8e-3 0.2 5.2e-3 -0.4 S198 ARKRRLSS TSLASGH - - - - - - - - - - - T199 RKRRLSST SLASGHS - - - - - - - - - - - S200 KRRLSSTS LASGHSV 0.53 - - 0.53 - - - - - - - S203 LSSTSLAS GHSVRLG 0.042 - - - - - - - - - 0.042 S206 TSLASGHS VRLGTSE -0.94 - - 0.75 - - - - 0.023 -6.5e-3 - T211 GHSVRLGT SESLPCT - - - - - - - - - - - S214 VRLGTSES LPCTAEE 9.2e-11 - -0.81 0.55 - 4.8e-5 2.3e-7 1.1e-3 -0.85 6.5e-5 0.1
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S183
S189
S197
S198
T199
S200
S203
S206
T211
S214
T218
S223
S225
S236
S238
S239
S240
S241
S242
S245
Y246
S353
S355
S362
S374
S375
Y378
S395
S396
S408
S518
S706
S710
T714
T853
S876
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation CCRCC S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation COAD S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation GBM S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation HNSCC S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation LSCC S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation LUAD S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation OV S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation PDAC S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation UCEC S183 S189 S197 S198 T199 S200 S203 S206 T211 S214 T218 S223 S225 S236 S238 S239 S240 S241 S242 S245 Y246 S353 S355 S362 S374 S375 Y378 S395 S396 S408 S518 S706 S710 T714 T853 S876 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S183
S189
S197
S198
T199
S200
S203
S206
T211
S214
T218
S223
S225
S236
S238
S239
S240
S241
S242
S245
Y246
S353
S355
S362
S374
S375
Y378
S395
S396
S408
S518
S706
S710
T714
T853
S876
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S183
S189
S197
S198
T199
S200
S203
S206
T211
S214
T218
S223
S225
S236
S238
S239
S240
S241
S242
S245
Y246
S353
S355
S362
S374
S375
Y378
S395
S396
S408
S518
S706
S710
T714
T853
S876
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.