OTUD4: OTU deubiquitinase 4
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S199 EVADEDNS EISDSED 3 32 14 - 5 4 - - - - - - - - - - - - - - 7 2 S202 DEDNSEIS DSEDDSC 3 27 9 - 5 4 - - - - - - - - - - - - - - 7 2 S341 PESWNTVS GKKMKKP 2 15 - - - - - - - - - - - - 5 4 - - 4 2 - - S349 GKKMKKPS TSGQNFH 1 18 - - - - - - 18 - - - - - - - - - - - - - T350 KKMKKPST SGQNFHS 2 18 - - - - - - 10 - 5 3 - - - - - - - - - - S351 KMKKPSTS GQNFHSD 1 10 - - - - - - - - 7 3 - - - - - - - - - - S385 PPRLQHPS GVRQHAF 8 335 26 - 9 8 - - - - 26 19 24 22 60 56 14 3 14 7 43 4 S399 FSSHSSGS QSQKFSS 2 18 - - - - - - 9 - - - - - 5 4 - - - - - - S401 SHSSGSQS QKFSSEH 1 18 - - - - - - 18 - - - - - - - - - - - - - T414 EHKNLSRT PSQIIRK 1 10 - - - - - - - - - - - - - - - - - - 10 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S199 EVADEDNS EISDSED - - - - - - - - - - - S202 DEDNSEIS DSEDDSC - - - - - - - - - - - S341 PESWNTVS GKKMKKP - - - - - - - - - - - S349 GKKMKKPS TSGQNFH - - - - - - - - - - - T350 KKMKKPST SGQNFHS - - - - - - - - - - - S351 KMKKPSTS GQNFHSD - - - - - - - - - - - S385 PPRLQHPS GVRQHAF 1.9e-13 - - - - 3.5e-3 0.01 4.3e-13 - - - S399 FSSHSSGS QSQKFSS - - - - - - - - - - - S401 SHSSGSQS QKFSSEH - - - - - - - - - - - T414 EHKNLSRT PSQIIRK - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S199
S202
S341
S349
T350
S351
S385
S399
S401
T414
S416
S443
S483
S495
T509
S517
S545
S546
S548
S557
S893
S900
S905
S922
S1006
S1011
S1023
S1024
Y1047
S1049
S1080
S1103
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation CCRCC S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation COAD S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation GBM S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation HNSCC S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation LSCC S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation LUAD S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation OV S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation PDAC S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation UCEC S199 S202 S341 S349 T350 S351 S385 S399 S401 T414 S416 S443 S483 S495 T509 S517 S545 S546 S548 S557 S893 S900 S905 S922 S1006 S1011 S1023 S1024 Y1047 S1049 S1080 S1103 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S199
S202
S341
S349
T350
S351
S385
S399
S401
T414
S416
S443
S483
S495
T509
S517
S545
S546
S548
S557
S893
S900
S905
S922
S1006
S1011
S1023
S1024
Y1047
S1049
S1080
S1103
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S199
S202
S341
S349
T350
S351
S385
S399
S401
T414
S416
S443
S483
S495
T509
S517
S545
S546
S548
S557
S893
S900
S905
S922
S1006
S1011
S1023
S1024
Y1047
S1049
S1080
S1103
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.