CHD9: chromodomain helicase DNA binding protein 9
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S155 HSMHQNKS FVAHHDF 1 10 - - - - - - - - - - 5 5 - - - - - - - - S550 RNIPRVMS PENFPTA 8 1131 - - 76 64 65 61 90 - 108 62 73 67 106 97 - - 105 44 95 18 S611 KQKRKNES SDEISDA 8 632 - - 12 2 27 26 81 - 6 3 93 85 70 65 - - 92 38 29 3 S612 QKRKNESS DEISDAE 8 810 - - 99 76 27 26 81 - 17 9 93 85 70 65 - - 92 38 29 3 S616 NESSDEIS DAEQMPQ 8 518 - - 21 20 27 26 81 - 17 9 5 4 70 65 - - 92 38 30 13 S654 EDIEGKQS EEEVKGS 8 997 - - 79 73 19 17 99 - 87 49 83 76 106 97 - - 88 34 72 18 T1447 RNSLVIDT PRIRKQT 1 9 - - - - - - - - - - - - - - - - - - - 9 S1458 RKQTRPFS ATKDELA 3 41 - - - - - - - - 5 3 - - - - - - 5 3 23 2 S1468 KDELAELS EAESEGD 8 571 - - 25 22 58 58 99 - 78 44 5 5 13 13 - - 100 43 8 - S1472 AELSEAES EGDEKPK 8 678 - - 61 56 58 58 9 - 78 47 75 66 23 19 - - 26 12 72 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S155 HSMHQNKS FVAHHDF - - - - - - - - - - - S550 RNIPRVMS PENFPTA 0.65 - 4.2e-7 -0.088 - -7.8e-5 0.1 3.4e-11 - -2.9e-4 -1.4e-7 S611 KQKRKNES SDEISDA 1.9e-28 - - 6.2e-4 - - 3.6e-13 3e-9 - 3.8e-8 - S612 QKRKNESS DEISDAE 5.9e-24 - 0.27 6.2e-4 - - 1.1e-12 4.1e-9 - 4.5e-7 - S616 NESSDEIS DAEQMPQ 1.1e-11 - -0.58 6.2e-4 - - - 3.8e-9 - 4e-7 0.18 S654 EDIEGKQS EEEVKGS 9.4e-21 - 6.4e-8 - - 2.7e-12 1.5e-8 5.4e-16 - -0.037 -0.23 T1447 RNSLVIDT PRIRKQT - - - - - - - - - - - S1458 RKQTRPFS ATKDELA - - - - - - - - - - - S1468 KDELAELS EAESEGD -0.93 - -0.035 0.014 - 1.4e-3 - - - -1.9e-4 - S1472 AELSEAES EGDEKPK 1.5e-8 - -4.8e-7 0.014 - 5.1e-6 1e-15 6.2e-4 - 0.36 0.53
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S155
S550
S611
S612
S616
S654
T1447
S1458
S1468
S1472
S1753
S1754
T2013
S2024
S2026
S2030
S2058
S2059
S2063
S2075
S2079
T2113
S2286
S2303
Y2382
S2554
S2745
S2747
S2750
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation CCRCC S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation COAD S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation GBM S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation HNSCC S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation LSCC S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation LUAD S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation OV S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation PDAC S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation UCEC S155 S550 S611 S612 S616 S654 S1458 S1468 S1472 S1753 S1754 T2013 S2024 S2026 S2030 S2058 S2059 S2063 S2075 S2079 T2113 S2286 S2303 Y2382 S2554 S2745 S2747 S2750 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S155
S550
S611
S612
S616
S654
T1447
S1458
S1468
S1472
S1753
S1754
T2013
S2024
S2026
S2030
S2058
S2059
S2063
S2075
S2079
T2113
S2286
S2303
Y2382
S2554
S2745
S2747
S2750
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S155
S550
S611
S612
S616
S654
T1447
S1458
S1468
S1472
S1753
S1754
T2013
S2024
S2026
S2030
S2058
S2059
S2063
S2075
S2079
T2113
S2286
S2303
Y2382
S2554
S2745
S2747
S2750
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.