KLC2: kinesin light chain 2
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
3ceq chain A
3ceq chain B
3edt chain B
3edt chain D
3edt chain F
3edt chain H
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S151 RKLDEDAS PNEEKGD 9 1269 122 - 103 80 28 17 99 - 108 62 108 99 101 93 - - 105 44 82 18 S175 FPNEDEQS PAPSPGG 7 184 9 - 13 12 - - 98 - - - 5 4 9 7 - - 10 3 11 3 S179 DEQSPAPS PGGGDVS 8 301 16 - 13 12 - - 93 - 36 20 15 14 19 15 - - 10 3 28 7 S328 PDVAKQLS NLALLCQ 4 109 9 - - - - - - - - - 25 22 19 16 - - - - 18 - S403 AHEKEFGS VNGDNKP 2 18 9 - - - - - - - - - - - - - - - - - 7 2 S428 SKDKRRDS APYGEYG 10 880 87 - 54 35 20 24 99 - 92 52 84 76 38 38 8 1 105 44 18 5 Y431 KRRDSAPY GEYGSWY 1 3 - - - - - - - - - - - - - - - - 2 1 - - S436 APYGEYGS WYKACKV 1 7 - - - - - - - - - - - - 4 3 - - - - - - S445 YKACKVDS PTVNTTL 10 676 38 - 5 4 14 13 80 - 35 19 44 43 69 64 43 8 61 28 90 18 S454 TVNTTLRS LGALYRR 1 8 - - - - - - - - - - - - 4 4 - - - - - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S151 RKLDEDAS PNEEKGD 1.7e-20 - -3.8e-11 -7.5e-3 - 2.2e-14 3e-28 1.6e-26 - 0.31 4.6e-4 S175 FPNEDEQS PAPSPGG - - - - - - - - - - - S179 DEQSPAPS PGGGDVS -0.05 - - - - -0.05 - - - - - S328 PDVAKQLS NLALLCQ 7.6e-4 - - - - - 7.6e-4 - - - - S403 AHEKEFGS VNGDNKP - - - - - - - - - - - S428 SKDKRRDS APYGEYG 6.6e-25 - 3e-11 0.7 - 2.3e-9 1.1e-4 0.11 - 1.3e-11 - Y431 KRRDSAPY GEYGSWY - - - - - - - - - - - S436 APYGEYGS WYKACKV - - - - - - - - - - - S445 YKACKVDS PTVNTTL 1.4e-16 - - - - 2.3e-3 5.9e-4 2.1e-5 - 5.2e-3 7.7e-7 S454 TVNTTLRS LGALYRR - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S151
S175
S179
S328
S403
S428
Y431
S436
S445
S454
T470
S487
S507
S508
S519
S521
T529
S537
S539
S545
S556
S557
T568
S581
S582
S589
S604
S608
S609
S610
S611
S615
S618
S619
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation CCRCC S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation COAD S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation GBM S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation HNSCC S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation LSCC S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation LUAD S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation OV S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation PDAC S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation UCEC S151 S175 S179 S328 S403 S428 Y431 S436 S445 S454 T470 S487 S507 S508 S519 S521 T529 S537 S539 S545 S556 S557 T568 S581 S582 S589 S604 S608 S609 S610 S611 S615 S618 S619 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S151
S175
S179
S328
S403
S428
Y431
S436
S445
S454
T470
S487
S507
S508
S519
S521
T529
S537
S539
S545
S556
S557
T568
S581
S582
S589
S604
S608
S609
S610
S611
S615
S618
S619
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S151
S175
S179
S328
S403
S428
Y431
S436
S445
S454
T470
S487
S507
S508
S519
S521
T529
S537
S539
S545
S556
S557
T568
S581
S582
S589
S604
S608
S609
S610
S611
S615
S618
S619
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.