PSMC6: proteasome 26S subunit, ATPase 6
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
5gjq chain L
5gjr chain L
5gjr chain z
5l4g chain L
5ln3 chain L
5m32 chain f
5t0c chain AE
5t0c chain BE
5t0g chain E
5t0h chain E
5t0i chain E
5t0j chain E
5vfp chain E
5vfq chain E
5vfr chain E
5vfs chain E
5vft chain E
5vfu chain E
5vgz chain E
5vhf chain E
5vhh chain E
5vhi chain E
5vhj chain E
5vhm chain E
5vhn chain E
5vho chain E
5vhp chain E
5vhq chain E
5vhr chain E
5vhs chain E
6msb chain E
6msd chain E
6mse chain E
6msg chain E
6msh chain E
6msj chain E
6msk chain E
6wjn chain E
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S123 DPLVYNMS HEDPGNV 1 8 - - - - - - - - 5 3 - - - - - - - - - - S131 HEDPGNVS YSEIGGL 2 41 9 - - - - - - - 20 12 - - - - - - - - - - Y132 EDPGNVSY SEIGGLS 1 18 - - - - - - - - - - - - 10 8 - - - - - - S244 AIGGRRFS EGTSADR 10 536 40 - 7 7 11 7 53 - 31 14 64 61 82 72 55 12 8 2 10 -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S123 DPLVYNMS HEDPGNV - - - - - - - - - - - S131 HEDPGNVS YSEIGGL -0.92 - - - - -0.92 - - - - - Y132 EDPGNVSY SEIGGLS - - - - - - - - - - - S244 AIGGRRFS EGTSADR 0.003 - - - - 0.23 0.022 3.5e-3 -0.64 - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S123
S131
Y132
S244
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S123 S131 Y132 S244 protein RNA SCNV methylation CCRCC S123 S131 Y132 S244 protein RNA SCNV methylation COAD S123 S131 Y132 S244 protein RNA SCNV methylation GBM S123 S131 Y132 S244 protein RNA SCNV methylation HNSCC S123 S131 Y132 S244 protein RNA SCNV methylation LSCC S123 S131 Y132 S244 protein RNA SCNV methylation LUAD S123 S131 Y132 S244 protein RNA SCNV methylation OV S123 S131 Y132 S244 protein RNA SCNV methylation PDAC S123 S131 Y132 S244 protein RNA SCNV methylation UCEC S123 S131 Y132 S244 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S123
S131
Y132
S244
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S123
S131
Y132
S244
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.