TNRC6B: trinucleotide repeat containing adaptor 6B
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S54 LSQPTAAS PIGSSPS 3 97 - - - - - - - - - - 5 5 - - - - 4 1 66 16 S58 TAASPIGS SPSPPVN 1 6 - - - - - - - - - - - - - - - - 4 2 - - S61 SPIGSSPS PPVNGGN 5 115 17 - - - - - - - - - 5 4 18 16 - - 10 3 31 11 S195 DKVIVDGS DMEEWPC 3 104 14 - 4 4 - - - - - - 42 40 - - - - - - - - S212 SKDTESSS ENTTDNN 2 19 - - - - - - - - - - 5 5 5 4 - - - - - - T215 TESSSENT TDNNSAS 1 9 - - - - - - - - - - - - 5 4 - - - - - - S220 ENTTDNNS ASNPGSE 1 9 - - - - - - - - - - - - 5 4 - - - - - - S226 NSASNPGS EKSTLPG 2 18 - - - - - - - - - - 5 4 5 4 - - - - - - S273 KSVQSSNS TTENNNG 1 26 - - - - - - - - - - - - - - - - - - 13 13 T378 DGPKNGNT NSLNLSS 1 13 - - - - - - - - - - - - - - - - 8 5 - -
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S54 LSQPTAAS PIGSSPS 9.5e-6 - - - - - - - - - 9.5e-6 S58 TAASPIGS SPSPPVN - - - - - - - - - - - S61 SPIGSSPS PPVNGGN -0.035 - - - - - - - - - -0.035 S195 DKVIVDGS DMEEWPC -4.0e-4 - - - - - -4.0e-4 - - - - S212 SKDTESSS ENTTDNN - - - - - - - - - - - T215 TESSSENT TDNNSAS - - - - - - - - - - - S220 ENTTDNNS ASNPGSE - - - - - - - - - - - S226 NSASNPGS EKSTLPG - - - - - - - - - - - S273 KSVQSSNS TTENNNG - - - - - - - - - - - T378 DGPKNGNT NSLNLSS - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S54
S58
S61
S195
S212
T215
S220
S226
S273
T378
S384
S385
S406
S421
S424
S456
S472
S483
S491
S507
S533
S562
S563
S564
T565
S567
S573
T574
S576
S592
Y593
T596
T606
S609
T611
S663
S686
S706
S707
S720
S721
S803
S815
S879
S882
S884
T941
S1011
S1067
S1073
S1086
T1213
S1220
S1302
S1336
S1338
S1432
Y1434
T1444
T1449
S1455
S1461
S1504
T1509
T1511
S1512
S1539
S1570
S1612
S1816
S1830
S1832
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation CCRCC S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation COAD S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation GBM S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation HNSCC S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation LSCC S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation LUAD S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation OV S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation PDAC S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation UCEC S54 S58 S61 S195 S212 T215 S220 S226 S273 T378 S384 S385 S406 S421 S424 S456 S472 S483 S491 S507 S533 S562 S563 S564 T565 S567 S573 T574 S576 S592 Y593 T596 T606 S609 T611 S663 S686 S706 S707 S720 S721 S803 S815 S879 S882 S884 T941 S1011 S1067 S1073 S1086 T1213 S1220 S1302 S1336 S1338 S1432 Y1434 T1444 T1449 S1455 S1461 S1504 T1509 T1511 S1512 S1539 S1570 S1612 S1816 S1830 S1832 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S54
S58
S61
S195
S212
T215
S220
S226
S273
T378
S384
S385
S406
S421
S424
S456
S472
S483
S491
S507
S533
S562
S563
S564
T565
S567
S573
T574
S576
S592
Y593
T596
T606
S609
T611
S663
S686
S706
S707
S720
S721
S803
S815
S879
S882
S884
T941
S1011
S1067
S1073
S1086
T1213
S1220
S1302
S1336
S1338
S1432
Y1434
T1444
T1449
S1455
S1461
S1504
T1509
T1511
S1512
S1539
S1570
S1612
S1816
S1830
S1832
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S54
S58
S61
S195
S212
T215
S220
S226
S273
T378
S384
S385
S406
S421
S424
S456
S472
S483
S491
S507
S533
S562
S563
S564
T565
S567
S573
T574
S576
S592
Y593
T596
T606
S609
T611
S663
S686
S706
S707
S720
S721
S803
S815
S879
S882
S884
T941
S1011
S1067
S1073
S1086
T1213
S1220
S1302
S1336
S1338
S1432
Y1434
T1444
T1449
S1455
S1461
S1504
T1509
T1511
S1512
S1539
S1570
S1612
S1816
S1830
S1832
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.