Protein: ENSP00000403644

DDC:: dopa decarboxylase

Lollipop plot

Phosphosites location and occurrence

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* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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				BRCA		CCRCC		COAD		GBM		HNSCC		LSCC		LUAD		OV		PDAC		UCEC
Site	Sequence	Cohorts	Total	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N	T	N
S149	GVIQGSASEATLVAL	1	29	-	-	16	13	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S171	IHRLQAASPELTQAA	1	23	-	-	12	11	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S220	GNFAMRASALQEALE	1	183	-	-	103	80	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
S340	LKHSHQDSGLITDYR	1	9	-	-	5	4	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 4 of 4 rows

Tumor and normal comparison

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Site	Sequence	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
S149	GVIQGSASEATLVAL	-	-	-	-	-	-	-	-	-	-	-
S171	IHRLQAASPELTQAA	-	-	-	-	-	-	-	-	-	-	-
S220	GNFAMRASALQEALE	-1.3e-27	-	-1.3e-27	-	-	-	-	-	-	-	-
S340	LKHSHQDSGLITDYR	-	-	-	-	-	-	-	-	-	-	-

Showing 1 to 4 of 4 rows

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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			Signed p-values
Phenotype	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
HALLMARK_FATTY_ACID_METABOLISM	S220	2.7e-6	-	2.7e-6	-	-	-	-	-	-	-	-
HALLMARK_BILE_ACID_METABOLISM	S220	3.2e-6	-	3.2e-6	-	-	-	-	-	-	-	-
HALLMARK_PEROXISOME	S220	5.9e-5	-	5.9e-5	-	-	-	-	-	-	-	-
HALLMARK_ADIPOGENESIS	S220	4.1e-4	-	4.1e-4	-	-	-	-	-	-	-	-
HALLMARK_PANCREAS_BETA_CELLS	S220	7.1e-4	-	7.1e-4	-	-	-	-	-	-	-	-
HALLMARK_HEME_METABOLISM	S220	1.7e-3	-	1.7e-3	-	-	-	-	-	-	-	-
HALLMARK_XENOBIOTIC_METABOLISM	S220	4.2e-3	-	4.2e-3	-	-	-	-	-	-	-	-
HALLMARK_OXIDATIVE_PHOSPHORYLATION	S220	4.9e-3	-	4.9e-3	-	-	-	-	-	-	-	-
PROGENy: VEGF	S220	0.014	-	0.014	-	-	-	-	-	-	-	-
xcell: Eosinophil	S171	0.02	-	0.02	-	-	-	-	-	-	-	-

Showing 1 to 10 of 1032 rows

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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			Signed p-values
Kinase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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			Signed p-values
Phosphatase	Site	Meta P	BRCA	CCRCC	COAD	GBM	HNSCC	LSCC	LUAD	OV	PDAC	UCEC
LPIN1	S171	-2.2e-16	-	-2.2e-16	-	-	-	-	-	-	-	-
OCRL	S220	-6.7e-4	-	-6.7e-4	-	-	-	-	-	-	-	-
SSH1	S220	-3.8e-3	-	-3.8e-3	-	-	-	-	-	-	-	-
IMPAD1	S220	-5.6e-3	-	-5.6e-3	-	-	-	-	-	-	-	-
UBASH3B	S220	-5.6e-3	-	-5.6e-3	-	-	-	-	-	-	-	-
PFKFB3	S220	-6.4e-3	-	-6.4e-3	-	-	-	-	-	-	-	-
PPIP5K2	S220	-0.01	-	-0.01	-	-	-	-	-	-	-	-
PTPN1	S220	-0.014	-	-0.014	-	-	-	-	-	-	-	-
PTPN12	S220	-0.016	-	-0.016	-	-	-	-	-	-	-	-
PPM1G	S149	-0.019	-	-0.019	-	-	-	-	-	-	-	-

Showing 1 to 10 of 960 rows

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Protein: ENSP00000403644Gene: DDC

Lollipop plot

Structure

Phosphosite detection coverage

Tumor and normal comparison

Phenotype and mutation association

Cis-association

Kinase association

Phosphatase association

Protein: ENSP00000403644
Gene: DDC