SUPT5H: SPT5 homolog, DSIF elongation factor subunit
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Structure
2do3 chain A
2e6z chain A
2e70 chain A
3h7h chain B
4l1u chain G
4l1u chain H
4l1u chain I
4l1u chain J
5oho chain A
5oho chain B
5ohq chain A
5oik chain Z
5u98 chain C
5u98 chain F
6eqy chain A
6er0 chain A
6gmh chain Z
6gml chain Z
6ted chain Z
7okx chain Z
7oky chain Z
7ol0 chain Z
7pks chain Z
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S15 NFSEEEDS ERSSDGE 1 9 - - - - - - - - 5 4 - - - - - - - - - - S18 EEEDSERS SDGEEAE 3 44 - - - - - - - - 5 4 15 14 - - - - - - 6 - S19 EEDSERSS DGEEAEV 3 44 - - - - - - - - 5 4 14 13 4 4 - - - - - - S32 EVDEERRS AAGSEKE 8 578 - - 64 49 7 2 18 - 103 59 78 73 46 41 - - 22 10 6 - S36 ERRSAAGS EKEEEPE 8 776 - - 30 20 56 51 46 - 103 58 94 82 25 23 - - 86 36 48 18 Y54 EEEEEEEY DEEEEEE 2 25 - - - - - - - - - - 5 5 - - - - 10 5 - - S108 EKEEIEAS NIDNVVL 6 365 46 - 45 27 - - - - 31 16 54 50 4 4 - - - - 81 7 S148 YMKKYAKS SVGETVY 6 107 - - 5 4 - - 9 - - - 15 15 9 8 - - 5 3 27 7 S149 MKKYAKSS VGETVYG 6 320 - - 12 12 - - 37 - 17 11 39 35 59 52 - - - - 30 16 S158 GETVYGGS DELSDDI 1 24 - - - - - - - - - - - - - - - - - - 13 11
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S15 NFSEEEDS ERSSDGE - - - - - - - - - - - S18 EEEDSERS SDGEEAE - - - - - - - - - - - S19 EEDSERSS DGEEAEV - - - - - - - - - - - S32 EVDEERRS AAGSEKE 2.2e-4 - -0.29 - - 0.12 2.4e-7 7.8e-7 - -0.02 - S36 ERRSAAGS EKEEEPE 1.7e-10 - -2.4e-5 1.6e-5 - 7.6e-7 2.8e-21 1.1e-7 - -0.01 -0.72 Y54 EEEEEEEY DEEEEEE - - - - - - - - - - - S108 EKEEIEAS NIDNVVL -0.57 - -3.3e-5 - - 0.75 4.4e-3 - - - - S148 YMKKYAKS SVGETVY - - - - - - - - - - - S149 MKKYAKSS VGETVYG -1.8e-5 - - - - - -2.4e-9 0.74 - - -0.074 S158 GETVYGGS DELSDDI - - - - - - - - - - -
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S15
S18
S19
S32
S36
Y54
S108
S148
S149
S158
T166
S354
S666
S670
S671
S676
S686
S755
T775
Y778
S780
S782
T784
Y787
T791
S797
T799
Y802
T806
S812
T814
T828
T1034
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation CCRCC S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation COAD S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation GBM S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation HNSCC S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation LSCC S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation LUAD S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation OV S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation PDAC S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation UCEC S15 S18 S19 S32 S36 Y54 S108 S148 S149 S158 T166 S354 S666 S670 S671 S676 S686 S755 T775 Y778 S780 S782 T784 Y787 T791 S797 T799 Y802 T806 S812 T814 T828 T1034 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S15
S18
S19
S32
S36
Y54
S108
S148
S149
S158
T166
S354
S666
S670
S671
S676
S686
S755
T775
Y778
S780
S782
T784
Y787
T791
S797
T799
Y802
T806
S812
T814
T828
T1034
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
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all sites
S15
S18
S19
S32
S36
Y54
S108
S148
S149
S158
T166
S354
S666
S670
S671
S676
S686
S755
T775
Y778
S780
S782
T784
Y787
T791
S797
T799
Y802
T806
S812
T814
T828
T1034
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.