DOCK4: dedicator of cytokinesis 4
Lollipop plot
Phosphosites location and occurrence
Select Y-axis:
Sample number
Cohort number
* Hover over the dots to see sequence motif and cohorts.
Phosphosite detection coverage
The frequency of phosphosite detection in the number of cohorts and tumor and normal samples
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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S901 TSRPQPSS SAMRFQF 1 8 - - - - - - - - - - 4 4 - - - - - - - - S902 SRPQPSSS AMRFQFQ 2 45 - - - - - - - - - - 10 10 13 12 - - - - - - S1599 FSACMQAS PVHFPNG 3 370 - - - - - - 90 - - - 98 90 48 44 - - - - - - S1607 PVHFPNGS PRVCRNS 2 82 - - - - - - 64 - - - 10 8 - - - - - - - - S1614 SPRVCRNS APASVSP 9 808 37 - 51 37 - - 80 - 31 22 103 94 110 101 49 7 24 9 37 16 S1618 CRNSAPAS VSPDGTR 4 81 - - 4 4 - - 18 - - - 24 22 4 5 - - - - - - S1620 NSAPASVS PDGTRVI 10 1277 90 - 79 57 65 70 99 - 96 56 108 99 106 97 70 15 93 39 29 9 S1631 TRVIPRRS PLSYPAV 10 1219 82 - 103 80 17 19 99 - 103 58 98 90 97 88 75 18 82 34 70 6 S1634 IPRRSPLS YPAVNRY 1 9 - - - - - - - - - - - - - - 8 1 - - - - S1700 APSSARAS PLLSDKH 10 1481 113 - 99 76 84 86 99 - 108 62 93 86 110 101 83 19 105 44 95 18
Tumor and normal comparison
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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S901 TSRPQPSS SAMRFQF - - - - - - - - - - - S902 SRPQPSSS AMRFQFQ - - - - - - - - - - - S1599 FSACMQAS PVHFPNG -1.6e-29 - - - - - -1.7e-23 -2.4e-9 - - - S1607 PVHFPNGS PRVCRNS - - - - - - - - - - - S1614 SPRVCRNS APASVSP -8.6e-26 - 2.8e-4 - - -2.1e-4 -1.8e-32 -3e-29 - - -0.75 S1618 CRNSAPAS VSPDGTR -2.2e-6 - - - - - -2.2e-6 - - - - S1620 NSAPASVS PDGTRVI -0.25 - 7.2e-17 0.09 - 4.4e-16 -5.5e-26 -5.8e-14 -0.093 0.015 - S1631 TRVIPRRS PLSYPAV -0.79 - 7.8e-17 - - 0.003 -4e-17 -7.3e-15 0.031 9.2e-4 - S1634 IPRRSPLS YPAVNRY - - - - - - - - - - - S1700 APSSARAS PLLSDKH -0.061 - 5.3e-27 0.012 - 1.1e-11 -3e-29 -3.4e-30 -0.29 4.9e-4 0.062
* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.
Phenotype and mutation association
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all sites
S901
S902
S1599
S1607
S1614
S1618
S1620
S1631
S1634
S1700
S1704
S1710
S1714
S1717
S1724
S1750
S1767
S1769
S1772
T1795
S1799
S1806
S1808
S1815
S1827
S1840
S1844
S1846
S1853
S1858
T1859
S1860
Y1887
S1897
T1899
S1921
S1926
S1941
all
clinical
pathway
cell type
genomic
mutation
Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.
Cis-association
BRCA S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation CCRCC S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation COAD S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation GBM S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation HNSCC S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation LSCC S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation LUAD S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation OV S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation PDAC S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation UCEC S901 S902 S1599 S1607 S1614 S1618 S1620 S1631 S1634 S1700 S1704 S1710 S1714 S1717 S1724 S1750 S1767 S1769 S1772 T1795 S1799 S1806 S1808 S1815 S1827 S1840 S1844 S1846 S1853 S1858 T1859 S1860 Y1887 S1897 T1899 S1921 S1926 S1941 protein RNA SCNV methylation
* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.
Kinase association
Protein
RNA
SCNV
methylation
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all sites
S901
S902
S1599
S1607
S1614
S1618
S1620
S1631
S1634
S1700
S1704
S1710
S1714
S1717
S1724
S1750
S1767
S1769
S1772
T1795
S1799
S1806
S1808
S1815
S1827
S1840
S1844
S1846
S1853
S1858
T1859
S1860
Y1887
S1897
T1899
S1921
S1926
S1941
Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.
Phosphatase association
Protein
RNA
SCNV
methylation
Loading, please wait
all sites
S901
S902
S1599
S1607
S1614
S1618
S1620
S1631
S1634
S1700
S1704
S1710
S1714
S1717
S1724
S1750
S1767
S1769
S1772
T1795
S1799
S1806
S1808
S1815
S1827
S1840
S1844
S1846
S1853
S1858
T1859
S1860
Y1887
S1897
T1899
S1921
S1926
S1941
Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found
* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.