Protein: ENSP00000404394
Gene: HDAC7

LinkedOmicsKB © 2022-2023 Zhang Lab

HDAC7:
histone deacetylase 7

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Structure

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S49SVEPMRLSMDTPMPE2189---------54--------
T52PMRLSMDTPMPELQV2246-----------108------
S109ERTVHPNSPGIPYRT10132799-9068596572-7444103941101018319102428418
S155FPLRKTVSEPNLKLR101529122-95809710090-10862108991101018319105448818
S181NPLLRKESAPPSLRR10124022-42379710099-10862938767628319105449518
S210STPASGCSSPNDSEH17--------52----------
S283PRGPILGSPHTPLFL6119----151218-6478----155254
T286PILGSPHTPLFLPHG71539-4463--301510101916----243
T356LHWPLSRTRSEPLPP468----4518---------135149
S358WPLSRTRSEPLPPSA101482122-7671838799-10359108991101018319105449518
Showing 1 to 10 of 20 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S49SVEPMRLSMDTPMPE-----------
T52PMRLSMDTPMPELQV-----------
S109ERTVHPNSPGIPYRT0.17-0.96-1.4e-3-0.88-5.5e-40.0950.0492.5e-90.45
S155FPLRKTVSEPNLKLR5.7e-4-2.1e-52.2e-20-7.7e-16-2.1e-19-1.1e-25-0.544e-16-3.5e-3
S181NPLLRKESAPPSLRR-0.023-0.150.031--0.75-1e-26-1e-211.2e-53.3e-13-7.5e-7
S210STPASGCSSPNDSEH-----------
S283PRGPILGSPHTPLFL-----------
T286PILGSPHTPLFLPHG-0.25-----0.25-----
T356LHWPLSRTRSEPLPP-----------
S358WPLSRTRSEPLPPSA-5.4e-15--2.3e-5-0.001-6.8e-3-6.1e-15-9e-15-0.39-0.340.94
Showing 1 to 10 of 20 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationCCRCCS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationCOADS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationGBMS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationHNSCCS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationLSCCS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationLUADS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationOVS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationPDACS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylationUCECS49T52S109S155S181S210S283T286T356S358S405S464S482S486S487S507S534S573S595S903proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.