Protein: ENSP00000405111
Gene: DHX57

LinkedOmicsKB © 2022-2023 Zhang Lab

DHX57:
DExH-box helicase 57

Lollipop plot

Phosphosites location and occurrence

Select Y-axis:

* Hover over the dots to see sequence motif and cohorts.

Phosphosite detection coverage

The frequency of phosphosite detection in the number of cohorts and tumor and normal samples

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BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
Site
Sequence
Cohorts
Total
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
T
N
S33GRSHASKSHGSGGGG117------------98------
S36HASKSHGSGGGGGGG117------------98------
S74FSESRRPSRPSNSNI91205112-4728928799-10160103949184--91376118
S77SRRPSRPSNSNISKG717264---1718-1062522----1054-
S105LQTLHMTSENQEKVK118------18-------------
S127EQDADAGSERGLSGE101389106-95729710099-10259989010293681573327018
S132AGSERGLSGEEEDDE10141276-103809710070-1086210393106977516105445918
S444VNFLPVPSRTRINNP832015---4527-26174542--277328218
T456NNPACHKTVIPNNSF14------------------4-
S462KTVIPNNSFVSNQIP258----------55------444
Showing 1 to 10 of 13 rows
1025
rows per page

Tumor and normal comparison

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Site
Sequence
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
S33GRSHASKSHGSGGGG-----------
S36HASKSHGSGGGGGGG-----------
S74FSESRRPSRPSNSNI0.002-3.4e-16-1.2e-11-9.5e-61.4e-11-0.42--0.87-6.9e-4
S77SRRPSRPSNSNISKG0.26-----0.26----
S105LQTLHMTSENQEKVK-----------
S127EQDADAGSERGLSGE8.1e-29-6.2e-59.3e-8-1.2e-41.3e-227.5e-230.056-4.4e-50.39
S132AGSERGLSGEEEDDE2.5e-7--2.8e-161.6e-17-3.3e-69.1e-195.9e-14-0.47-1.6e-130.17
S444VNFLPVPSRTRINNP3.9e-7----8.1e-47.9e-8---0.95
T456NNPACHKTVIPNNSF-----------
S462KTVIPNNSFVSNQIP-----------
Showing 1 to 10 of 13 rows
1025
rows per page

* P-values are from Wilcoxon rank sum test and can be clicked to show the box plots. Positive values mean higher abundance in tumor. BRCA and GBM do not have normal samples.

Phenotype and mutation association

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Signed p-values
Phenotype
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values could be from test for Spearman correlation, Wilcoxon rank sum test, Jonckheere-Terpstra trend test or Cox regression depending on the data type. P-values for individual cohorts can be clicked to show the data plots.

Cis-association

BRCAS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationCCRCCS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationCOADS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationGBMS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationHNSCCS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationLSCCS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationLUADS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationOVS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationPDACS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylationUCECS33S36S74S77S105S127S132S444T456S462S475S477S480proteinRNASCNVmethylation

* The circles can be clicked to show the scatter plots. The color and size of the circles correlate with the Spearman correlation coefficients.

Kinase association

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Signed p-values
Kinase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.

Phosphatase association

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Signed p-values
Phosphatase
Site
Meta P
BRCA
CCRCC
COAD
GBM
HNSCC
LSCC
LUAD
OV
PDAC
UCEC
No matching records found

* P-values are from test for Spearman correlation. P-values for individual cohorts can be clicked to show the data plots.